Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Systems 1 Part 2 > Restrictive Diseases > Flashcards

Restrictive Diseases Flashcards

1
Q

restrictive diseases have reduced lung volumes because of –

A

an alteration in lung parenchyma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

– and defects in chest wall or neuromuscular apparatus may also cause respiratory restrictions

A

pleural diseases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

risk factors associated with poorer outcomes

A

older age, male, h/o cigarette smoking

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

collagen vascular diseases

A

scleroderma, systemic lupus erythematosus (SLE), ankylosing spondylitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

environmental exposures

A

medications, dust, ionizing radiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Idiopathic fibrotic disorders –

A

idiopathic pulmonary fibrosis (IPF)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Infiltrative diseases -

A

sarcoidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

etiology of scleroderma

A

unknown

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

scleroderma involves – sclerosis

A

progressive systemic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

scleroderma is characterized by progressive interstitial fibrosis with atrophy and sclerosis of many organ systems such as

A

skin, internal organs, blood vessel walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

sclerodermic skin

A

leathery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

pulmonary scleroderma: –, sclerosis and progressive volume loss

A

diffuse interstitial infiltrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

CXR of pulmonary scleroderma

A

fibrocystic spaces (honeycomb) mostly at lung base

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

systemic lupus erythematosus is a disorder of –

A

immune regulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

SLE: tissues are damaged by –

A

autoantibodies and immune complexes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

SLE: antibodies are directed to –

A

blood, endothelial and neuronal cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

T/F: SLE is a significant cause of renal failure

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

cardiac manifestations of SLE

A

pericarditis and endocarditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

SLE may involve –, pneumonitis, interstitial lung diseases

A

pleural effusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

ankylosing spondylitis is a type of – of the axial skeleton

A

spondyloarthropathy

21
Q

ankylosing spondylitis is associated with –

A

human leukocyte antigen (HLA) B27

22
Q

hallmark of ankylosing spondylitis

A

new bone formation and joint ankyloses –> rigid or bamboo spine

23
Q

ankylosing spondylitis usually involves – sites

A

extra-articular

24
Q

disease at extra-articular sites include –, aortitis, aortic insufficiency, conjunctivitis and uveitis

A

pulmonary fibrosis

25
Q

swelling and irritation of the uvea

A

uveitis

26
Q

depending on the length of exposure, pulmonary inflammation and/or fibrosis leads to acute symptoms

A

cough

27
Q

depending on the length of exposure, pulmonary inflammation and/or fibrosis leads to chronic disease

A

dyspnea and weight loss

28
Q

pulmonary disease with certain medications

A

gold, Dilantin, bleomycin, methotrexate

29
Q

seen in sandblasters, stone cutters & concrete workers who are exposed to silica dust

A

silicosis

30
Q

– seen in mushrooms growers or farmers exposed to compost & peat moss or in factory workers exposed to plastics, resins or paints

A

hypersensitivity pneumonitis

31
Q

seen in coal miners

A

coal miner’s pneumoconiosis

32
Q

ionizing radiation due to occupational exposure or for cancer tx may lead to –

A

lung damage (edema –> fibrosis) and radiation pneumonia

33
Q

sarcoidosis – changes involving the lungs and many other organ systems

A

granulomatous tissue

34
Q

cause of sarcoidosis

A

unknown

35
Q

can sarcoidosis occur in salivary glands and oral mucosa?

A

yes

36
Q

higher prevalence of sarcoidosis among

A

women and African Americans

37
Q

idiopathic pulmonary fibrosis prevalence increases with –

A

age, smoking, exposure to dust, metals, organic solvents, agriculture employment

38
Q

clinical features of idiopathic pulmonary fibrosis

A

hypoxia and digital clubbing

39
Q

idiopathic pulmonary fibrosis patients may benefit from – in early stages

A

anti-inflammatories

40
Q

advanced idiopathic pulmonary fibrosis is associated with – and candidate for lung transplant

A

O2 dependency and poor prognosis

41
Q

symptoms and signs of idiopathic pulmonary fibrosis: progressive – especially with exercise

A

dyspnea

42
Q

symptoms and signs of idiopathic pulmonary fibrosis: cough (esp after deep breath) but – not likely

A

sputnum

43
Q

symptoms and signs of idiopathic pulmonary fibrosis: cyanosis is seen in –

A

late stages

44
Q

pulmonary function changes in idiopathic pulmonary fibrosis

A

decreased TV, VC, TLC

45
Q

treatment of idiopathic pulmonary fibrosis

A

treat underlying problem; corticosteroids and cytotoxic drugs

46
Q

common feature of restrictive diseases

A

interstitial pulmonary tissue involvement

47
Q

restrictive changes are associated with pulmonary manifestations such as –

A

dyspnea

48
Q

chronic restrictive diseases may lead to –

A

hypoxemia

49
Q

T/F: many restrictive disease conditions are irreversible

A

true

Systems 1 Part 2 (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions