Pathology of Pulmonary infections and Vascular Disease Flashcards
infection can be caused by aspiration due to –
abnormal mucociliary function, abnormal cough functions, immunocompromised patients
what are risk factors abnormal mucociliary function?
smokers, cystic fibrosis, other congential disease
what are risk factors of abnormal cough functions?
anesthesia, dementia, alcohol
examples of immunocompromised patients due to
cancer, transplantation, congenital immunodeficiency
most common type of organism associated with acute pneumonia
bacteria
fungi typically affect –
immunocompromised patients
fungal infection usually cause –
anatomic abnormality (cystic spaces or dilated airways)
mild viruses affect –
healthy patients
life threatening viruses affect –
less healthy patients
what type of organismal infection is rare in industrialized countries
parasites
exceptions to the typical viral mode of infection
HIN1 flu, SARS
pattern of disease of primary pneumonia
inhale or aspire organisms
pattern of disease of secondary pneumonia
hematogenous dissemination from infection in other site
need to distinguish infection from –
colonization
in lobar pneumonia the entire lobe is affected by –
inflammatory infiltrate
classic organism of lobular pneumonia
Streptococcus pneumoniae
lobular pneumonia aka
bronchopneumonia or focal pneumonia
lobular pneumonia is characterized by –
neutrophilic inflammation centered on respiratory bronchioles
alveolar spaces filled with acute inflammatory cells
lobular pneumonia
organism associated with community-acquired pneumonia
streptococcus pneumoniae
community acquired atypical pneumonia
Mycoplasma pneumonia and viral agents
T/F: hospital acquired pneumonia is usually seen patients with severe underlying disease
true
oragnisms associated with hospital acquired pneumonia
MRSA, Gram negative bacilli, anaerobes
risk factors for hospital acquired pneumonia: old age, – , disposition to aspiration, contaminated respiratory equipment, colonization after thoracic surgery
immunosuppression