Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Systems 1 Part 2 > Histology and pathology of lung diseases > Flashcards

Histology and pathology of lung diseases Flashcards

1
Q

properties of right bronchus

A

more vertically oriented

more frequent aspiration site

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

arteries follow –

A

airways

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T/F: infarctions are common

A

false

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

normal epithelium of the upper respiratory tract and large airways

A

pseudostratified ciliated columnar epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

most common cell type in pseudostratified ciliated columnar epithelium

A

ciliated cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

cell types in pseudostratified ciliated columnar epithelium

A

ciliated, secretory, and those that don’t reach luminal surface

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

secretory cells of pseudostratified ciliated columnar epithelium

A

mucous (goblet) and club (Clara) cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

cells that don’t reach luminal surface

A

basal (stem), Kulchitsky, and serous cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Most common secretory cell

A

mucous (goblet)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Most common secretory cells in terminal and respiratory bronchioles

A

club (Clara) cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

function of club cells

A

secretes proteins that protect the bronchiolar lining

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

function of Kulchitsky cell

A

secretes peptide hormones (especially serotonin) to regulate vascular tone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

where are serous cells located?

A

submucosal glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

function of serous cells

A

secrete bactericidal proteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is in the bronchus?

A

cartilage and submucosal glands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

can the bronchus collapse?

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Can the bronchiole collapse?

A

yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

usually the bronchiole is the same size as the –

A

pulmonary artery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

T/F: type 1 pneumocyte are flat cells that is a minor lining cell but covers about 97% of alveolar surface

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

type 2 pneumocyte cover – of alveolar surface

A

3%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what is the alveolar reserve cell

A

pneumocyte type 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

T/F: lymphatic channels and stromal cells are scarce

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

type 2 alveolar cells are – of epithelial cells

A

60%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

which cells can divide during repair?

A

type 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
can type 1 flat cells divide?
no
26
which type of lung disease is more common?
obstuctive
27
obstructive pulmonary disease can be determined by --
pulmonary function test
28
obstructive disease is due to --
airway narrowing (structural) or loss of elastic recoil (functional)
29
who usually has asthma?
children to young adults
30
who usually has chronic bronchitis and emphysema
older smoking men
31
histology of asthma
EOSINOPHILS, mucostasis, SM hyperplasia, BM thickening
32
histology of chronic bronchitis
chronic inflammation, goblet cell hyperplasia, increase in submucosal glands
33
Chronic bronchitis histology looks like asthma without --
eosinophils
34
chronic bronchitis: large airways
mucous overproduction
35
chronic bronchitis: small airways
scarring
36
T/F: lungs are last organs to dev and first to deteriorate
true
37
most common form of emphysema
centrilobular
38
emphysema: damage to alveolar walls adjacent to respiratory bronchioles results in --
loss of alveolar tissue nd large empty airspaces
39
T/F: small airway fibrosis is present in emphysema and chronic bronchitis
true
40
-- emphysema is observed in alpha-1-antitrypsin deficiency
panacinar (panlobular)
41
which part of the lung is worse in emphysema
upper lobe
42
-- is required to supplement expiration and hold open small airways
elasticity
43
loss of elasticity results in -- obstruction
functional and structural
44
all obstructive disease results in -- in expiratory airflow
decrease
45
in obstructive disease, lung volume may be increased but -- is decreased
forced expiratory volume in one second (FEV1)
46
restrictive disease is defined by --
reduced lung capacity (reduced volume or decrease in expansion)
47
T/F: in restrictive lung disease, expiratory function may be normal or reduced
true
48
causes of restrictive lung disease
intrinsic: infiltrative process in interstitium or extrinsic: chest wall disorder, neuromuscular disorder, obesity
49
there are many different causes for restrictive lung disease but almost half are --
idiopathic
50
diffuse infiltrative lung disease results in -- that are difficult to expand --> restrictive lung disease
firm, less pliable lungs
51
in normal lung, the interstitium is -- and consists of capillaries and a few cells in the alveolar wall
inconspicuous
52
in interstitial lung disease, the intersitium is -- and lung loses its inherent pliability
expanded by fibrosis or cells
53
usual interstitial pneumonia (50-70 y/o male)
temporally and spatially heterogeneous pattern of chronic interstitial inflammation and fibrosis
54
prognosis of UIP
poor 3-5 years
55
risk factors of UIP
idiopathic, genetic and environmental risk factors
56
what replaces fibrosis?
scar tissue
57
nonspecific interstitial pneumonia has a pattern of --
uniform septal thickening
58
nonspecific interstitial pneumonia: interstitial inflammation full of --
cells or fibrosis
59
nonspecific interstitial pneumonia can be --
primary or secondary
60
secondary causes of nonspecific interstitial pneumonia
collagen vascular disease (like lupus), durgs, infection
61
mimickers of nonspecific interstitial pneumonia
lymphoma
62
hypersensitivity pneumonitis: hypersensitivity reaction to an inhaled antigen results in --
chronic bronchocentric inflammation
63
acute hypersensitivity pneumonitis is due to --
type III hypersensitivity
64
chronic hypersensitivity pneumonitis is due to --
type IV hypersensitivity
65
common agents of hypersensitivity pneumonitis
parakeet, fungi in mold, humidifiers etc
66
symptoms of hypersensitivity pneumonitis
dyspnea, fever, malaise, weight loss, clubbing
67
histologic feature of hypersensitivity pneumonitis
poorly formed granuloma = giant cell
68
systemic non-necrotizing granulomatous disease that can affect every organ
sarcoidosis
69
sarcoidosis: usual sites of granulomas are --
mediastinal lymph nodes, lungs, liver
70
T/F: sarcoidosis has great variation in lung disease manifestations from minimal subclinical to severe interstitial fibrosis
true
71
sarcoidosis is a disease of --
exclusion
72
histologic feature of sarcoidosis
well-formed non-necrotizing granulomas
73
histology color of sarcoidosis
dense pink fibrosis

Systems 1 Part 2 (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions