Renal 3 Flashcards

1
Q

in the absence of vasopressin, the cortical and medullary collecting ducts are – to water

A

impermeable

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

without vasopressin, the osmolarity of tubular fluid would remain – than that of plasma

A

less

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

renin is secreted by – of kidneys

A

juxtaglomerular cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

renin – the removal of angiotensin I from angiotensinogen

A

catalyzes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

conversion of Ang I to Ang II stimulates –

A

secretion of aldosterone from adrenal cortex

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

– directly innervates juxtaglomerular cells and stimulates renin secretion

A

renal sympathetic nerves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

where are juxtaglomerular cells located at?

A

afferent arterioles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

juxtaglomerular cells are sensitive to pressure within arterioles so they act as –

A

intrarenal baroreceptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

effect of reduced plasma volume and low blood pressure in kidney on baroreceptor cells

A

stretched less –> secrete more renin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

layer of specialized epithelial cells located near the ends of the ascending loops of Henle

A

macula densa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

macula densa are closely juxtaposed to –

A

afferent arteriole and juxtaglomerular cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

macula densa is a –

A

chemoreceptor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

macula densa sense – in tubule flowing past it

A

Na+ and/or Cl- concentration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

– concentration of Na+/Cl- cause macula densa to stimulate juxtaglomerular cells to secrete renin

A

decreased

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

three inputs controlling renin secretion

A

renal sympathetic nerves
juxtaglomerular cells as baroreceptors
macula densa as chemoreceptors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

– CV pressure leads to increased vasopressin

A

decreased

17
Q

– plasma osmolarity leads to increased vasopressin

A

increased

18
Q

low plasma volume –> venous, atrial, and arterial pressures

A

decrease

19
Q

which renal process is controlled for K+?

A

secretion

20
Q

where does secretion of K+ occur?

A

cortical collecting ducts

21
Q

effect of high plasma K+ on adrenal cortex

A

increase aldosterone secretion

22
Q

increased plasma effect on cortical collecting ducts

A

increased K+ secretion and excretion

23
Q

two major controls of aldosterone secretion

A

[plasma angiotensin II] and [plasma K+]

24
Q

aldosterone induces – in luminal membrane of cortical collecting-duct cells

A

synthesis of Na+ and K+ channels

25
Q

aldosterone induces – in cells’ basolateral membrane

A

Na/K-ATPase pumps

26
Q

aldosterone increase reabsorption of – in cortical collecting ducts and decrease its excretion

A

Na+

27
Q

aldosterone increase secretion of – in cortical collecting ducts and increase its excretion

A

K+

28
Q

ANP increases –

A

Na+ excretion

29
Q

ANP is a hormone synthesized in –

A

cardiac atria

30
Q

ANP is released to in response to –

A

increased Na+ and increased blood plasma volume

31
Q

ANP inhibits – at tubules by inhibiting aldosterone production

A

sodium reabsorption

32
Q

ANP increases – which increase sodium excretion

A

GFR

33
Q

T/F: both aldosterone and ANP are hormonal responses designed to maintain blood volume and pressure

A

true

34
Q

hypertension is generally caused by the kidneys’ – in response to normal blood pressure

A

inability to excrete Na+