Control of Breathing 2 Flashcards

1
Q

muscle spindles are abundant in muscles of the –

A

chest wall

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2
Q

muscle stretch activates spindle afferent fibers causing –

A

reflex extrafusal fiber contraction (alpha-efferent activation)

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3
Q

intrafusal fiber contraction (gamma-efferent activation) – stretch response

A

amplifies

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4
Q

muscle spindles sense – of muscles of respiration

A

elongation

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5
Q

muscle spindles may contribute to – during bronchospasm where increased efforts are needed to generate a breath

A

sense of dyspnea

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6
Q

mechanoreceptors in the joint and muscles detect –

A

limb movement

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7
Q

mechanoreceptors instruct the inspiratory center to –

A

increase breathing rate

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8
Q

mechanoreceptors are important for – response to exercise

A

early (anticipatory) ventilator

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9
Q

cough receptors are rapidly adapting irritant receptors on the –

A

mucosa of lung

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10
Q

stimulated cough receptors send impulses to –

A

internal laryngeal nerve to vagus

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11
Q

impulse send to internal laryngeal nerve and vagus nerve stimulate – then the impulses travel back to respiratory muscles and bronchioles

A

brainstem

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12
Q

deep breath in, larynx –

A

closes

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13
Q

deep breath in –>

A

high pressure and accessory muscles contract

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14
Q

after accessory muscles contract, – and air is forced out rapidly (cough)

A

larynx and glottis open

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15
Q

during cough, airways – to focus beam of air and flush out irritants

A

narrow

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16
Q

what is atelectasis?

A

alveolar collapse

17
Q

what usually prevents atelectasis (alveolar collapse)?

A

surfactant

18
Q

response to atelectasis (alveolar collapse)

A

sighs

19
Q

during sighs, – accumulate in pre-Botzinger complex

A

neuropeptides

20
Q

accumulated neuropeptides in pre-Botzinger complex trigger –

A

breath stack

21
Q

what is a breath stack?

A

second inspiration before completed expiration

22
Q

during sighs, there is a – of lung and recruitment of atelectatic alveoli

A

hyperinflation

23
Q

ventilation during sleep is under – control

A

automatic

24
Q

ventilation during sleep is driven by –

A

changes in PaCO2

25
Q

sleep onset leads to – in central ventilatory drive

A

decrease

26
Q

sleep onset leads to – in muscle tone

A

decrease

27
Q

sleep onset leads to – ventilator responsiveness

A

decrease

28
Q

sleep leads to increase in –

A

PaCO2 and pulmonary artery pressure

29
Q

partial obstruction of airway during sleep leads to –

A

snoring

30
Q

no airflow during sleep and desaturating

A

central sleep apnea

31
Q

trying to breathe during sleep and desaturating

A

obstructive sleep apnea (more common)

32
Q

gold standard to treat sleep apnea

A

CPAP machine

33
Q

how to treat mild to moderate sleep apnea

A

dental devices

34
Q

how do dental devices treat sleep apnea?

A

open airway by pushing lower jaw, tongue, and soft tissue forward

35
Q

at high elevation (low O2) body produces more –

A

erythropoietin (so that we can carry the same amount of oxygen)

36
Q

carbonic anhydrase excrete bicarbonate urine –>

A

pH drop and makes you breathe faster = compensate for hypoxia