Respiratroy Tract Drugs: Asthma And COPD (79)

Question 1

Bronchial asthma

Answer 1

Recurrent and reversible shortness of breath
-lung airways narrow (bronchospasms, inflammation of bronchial mucosa)

Question 2

Bronchospasms are a response

Answer 2

To mechanicals released form immune system and secretions

Question 3

Airflow limitation is caused by

Answer 3

Bronchospasms and inflammation

Question 4

Bronchial asthma

Answer 4

Alveolar ducts/alveoli remain open but airflow is obstructed
-causing difficulty breathing or wheezing

Question 5

Status asthmaticus

Answer 5

Medical emergency
-prolonged asthma attack
-does not respond to usual medical therapy

Question 6

COPD

Answer 6

Chronic obstructive pulmonary disease
-obstruction is constantly present, but can vary in severit y

Question 7

Tobacco smoke and air pollution causes

Answer 7

Inflammation of the airway epithelium
-release of cytokines

Question 8

Chronic bronchitis is

Answer 8

Continous inflammation of the bronchi and bronchioles
-result of prolonged exposure to bronchial irritants

Question 9

Emphysema

Answer 9

Air spaces enlarge as a result of the destruction of alveolar walls
-surface area is reduced
-impaired res[iration

Question 10

Bronchodilator’s

Answer 10

-B2 adrenergic agonists
-anticholinergics
-can think derivatives

Question 11

B2 adrenergic agonists

Answer 11

Albutamol salbutamol

Question 12

Anticholinergics

Answer 12

Ipratropium bromide

Question 13

Xanthine derivatives

Answer 13

Theophylline/aminophylline

Question 14

Anti inflammatory drugs

Answer 14

-glucocorticoids
-leukotriene modifiers

Question 15

Issues with inhalers

Answer 15

Technique
-local effect and much quicker

Question 16

PO drug will interact with more

Answer 16

Receptors = more AE

Question 17

Bronchodilator’s: B agonists are

Answer 17

Sympathomimetic bronchodilators
-stimulate bronchial smooth muscle b2 andrenergic receptors

Question 18

Two types of smooth muscle b2 adrenergic receptor s

Answer 18

-short acting B agonists (SABA)

-long acting B agonists (LABA)q

Question 19

Selective b2 drugs

Answer 19

Activate airway smooth muscle b2 adrenergic receptors