Bipolar Disorder (36)

Question 1

What is the first line treatment of mani and manic depressive illness

Answer 1

Lithium

Question 2

Lithium MOA

Answer 2

Poor understanding of mechanism

Question 3

Lithium has a ____ therapeutic range (include numbers)

Answer 3

Narrow therapeutic range
0.4 and 1.5 mmol/L

Question 4

Toxicities at __ mmol/L and __ mmol/L

Answer 4

2,2.5

Question 5

Lithium adverse effects (less than 1.5 mmol/L)

Answer 5

-fine finger tremor
-polyuria and thirst
-GI upset

Question 6

Long term AE of lithium

Answer 6

Renal impairment, goitre, hypothyroidism

Question 7

Lithium toxicity level

Answer 7

Greater than 1.5mmol/L

Question 8

Symptoms of lithium toxicity

Answer 8

-persistent GI upset
-course hand tremor
-CNS effects

Question 9

What are newer drugs being used to react bipolar disorder

Answer 9

Valproate and carbamazepine