Respiratory System and Disorders- Notes from Slideshow (quiz 3) PART 2 Flashcards
Condition in which fluid collects in the lungs’ air sacs, depriving organs of oxygen. Can occur in those who are critically ill or who have significant injuries. It is often fatal, the risk increasing with age and severity of illness.
ARDS
Defining characteristics of ARDS
- It is in both lungs- bilateral disease
- Refractory to oxygen
- AVQ mismatch
What causes the ARDS “perfect storm”?
All of the inflammatory mediators have been sent out to cause this inflammatory response
Where does the problem associated with ARDS take place in the body?
Capillary membrane problem
What is the end result of ARDS?
- fluid collects in the lungs’ air sacs
2. deprives organs of oxygen.
Who gets ARDS?
- critically ill (infection)
2. have significant injuries
What sets this disease apart from pneumonia?
Pneumonia is on one side-ARDS is on both
If you intubate these pt in order to put them on 100% O2 what happens?
O2 level WONT go up
main symptom of ARDS
Severe SOB
Survival of pts with ARDS
Not many survive
Underlying causes of ARDS
- Major injury
- Inhalation of harmful substances
- Severe Infection (including covid)
- Pancreatitis
- Massive blood transfusions
- Burns
- Sepsis
- Inhalation of harmful substances
- Severe pneumonia
- Head, chest or other major injury
- Coronavirus disease 2019
- Pancreatitis
- Massive blood transfusions
- Burns
Underlying causes of ARDS
Pathophysiology of ARDS
- Injury to capillary membrane
- platelets aggregate
- inflammatory inflame
- damage alveolar membrane
- Fluids leak both ways
- Surfactant is lost
- Capillaries collapse
- Gas exchange impaired
- Fibrosis
- Hypoxemia leads to acidosis
- Injury to capillary membrane
- platelets aggregate
- inflammatory inflame
- damage alveolar membrane
- Fluids leak both ways
- Surfactant is lost
- Capillaries collapse
- Gas exchange impaired
- Fibrosis
- Hypoxemia leads to acidosis
Pathophysiology of ARDS
What does ARDS look like on a xray
Both lungs cloudy all over
A breathing disorder in newborns caused by immature lungs.
Infant Respiratory Distress Syndrome (IRDS)
At what age it it most common to see IRDS?
babies born at 37-39 weeks
At what age it it most uncommon to see IRDS?
babies born After 39 weeks
What causes IRDS?
lack of surfactant
What do these babies not have surfactant?
It has not developed yet before their born
What is surfactant
- Slippery substance in the lungs
- Helps the lungs fill with air
- Keep air sacs from deflating
Other than premature birth, what else can cause IRDS?
genetic problems with lung development
IRDS Symptoms
- Tachypnoea ( >60)
- Tachycardia (>160)
- Cyanosis
- Nasal Flaring
- Grunting
- Apnea/dyspnea
- Chest wall recessions (suprasternal, intercostal, subcostal)
- Tachypnoea ( >60)
- Tachycardia (>160)
- Cyanosis
- Nasal Flaring
- Grunting
- Apnea/dyspnea
- Chest wall recessions (suprasternal, intercostal, subcostal)
IRDS Symptoms
What does the teacher compare surfactant to?
Dish soap
What increases risk IRDS?
The more premature the higher the risk
What is surfactant composed of?
- phospholipid
- protein
- carbs
What produces and secretes surfactant?
Alveolar type II cells
What does surfactant do?
Lower surface tension
Characteristics of the lung in IRDS pts
- Rigid
- Edema
- Alveoli are collapse
One of two major types of lung cancer that can affect smokers and nonsmokers.
A group of lung cancers that behave similarly.
Non-Small Cell Lung Cancers
Types of Non-Small Cell Lung Cancers
- Adenocarcinoma
- Squamous Cell Carcinoma
- Large Cell Carcinoma
Adenocarcinoma vs. Squamous Cell Carcinoma vs. Large Cell Carcinoma: Defining characteristic
- Adenocarcinoma: Most common form
- Squamous Cell Carcinoma: Early symptoms
- Large Cell Carcinoma: Rapid growth and late symptoms
Adenocarcinoma vs. Squamous Cell Carcinoma vs. Large Cell Carcinoma: Origin
- Adenocarcinoma: Outer regions of lung
- Squamous Cell Carcinoma: Bronchial tubes
- Large Cell Carcinoma: Outer edges of lungs
Prevalence of each type of lung cancer
- Adenocarcinoma (40%)
- Squamous Cell Carcinoma (30%)
- Large Cell Carcinoma (15%)
- Small Cell lung cancer (15%)
Lung cancer symptoms
- Loss of appetite
- weight loss
- Difficulty breathing
- Chronic lung infections
- Chest pain that worsens with breathing
- Hoarseness
- Fatigue
- Persistent cough
- Night sweats
- Coughing up blood or phlegm
- Loss of appetite
- weight loss
- Difficulty breathing
- Chronic lung infections
- Chest pain that worsens with breathing
- Hoarseness
- Fatigue
- Persistent cough
- Night sweats
- Coughing up blood or phlegm
Lung cancer symptoms