Nervous System: Part 3

Question 1

Parkinson’s Disease

Answer 1

A degenerative disorder of basal ganglia function

Question 2

Cause of Parkinson’s Disease

Answer 2

Lack of dopamine

Question 3

Role of dopamine in Parkinson’s Disease

Answer 3

Dopamine gives us smoothness (fine motor coordination):

• Brdaykinesia
• rigidity

Question 4

Patho of Parkinson’s Disease

Answer 4

• Progressive destruction of the nigrostriatal pathway

- reduction in striatal concentrations of dopamine

Question 5

Symptoms of Parkinsonism

Answer 5

• blank facial expression
• forward tilt to posture
• slow, monotonous, slurred, speech
• reduced arm swinging
• rigidity and tremor of extremeties and head
• short, shuffling gait

Question 6

Amyotrophic Lateral Sclerosis is aka

Answer 6

• ALS

- Lou Gehrig’s Disease

Question 7

ALS

Answer 7

neurologic disorder that selectively affects motor function

Question 8

Years of survival from onset of symptoms of ALS?

Answer 8

2-5 years

Question 9

Progression of ALS

Answer 9

• usually starts in one single muscle group
• Slow
• progressive
• muscle weakness-strength and bulk diminish
• death of the lower motor neurons in the spinal cord and brain stem

Question 10

What causes ALS pts trouble at the end of their disease?

Answer 10

• Swallowing
• Speech
• Respiratory

Question 11

Multiple Sclerosis

Answer 11

Demyelinating disease of the CNS

Question 12

Who does MS effect?

Answer 12

-Most common nontraumatic cause of neurologic disability among young and middle-aged adults

Question 13

What is MS characterized by?

Answer 13

-exacerbations and remissions over many years -in several different sites in the CNS

Question 14

Progression of MS

Answer 14

• Initially, normal or near-normal neurologic function between exacerbations
• As disease progresses, there is less improvement between exacerbations
• increasing neurologic dysfunction

Question 15

Patho of MS

Answer 15

• WBC attack neurons
• Affect myelin in brain and spinal cord
• damages myelin leaves scarring (sclerosed)
• nerve signals slowed or blocked

Question 16

myelin

Answer 16

fatty tissues around nerve fibers

Question 17

A common first sign of MS

Answer 17

Try to get out of bed and they cant feel the floor

Question 18

Central Processing of Pain Information: Transmission to Somatosensory Cortex

Answer 18

Pain information perceived & interpreted

Question 19

Central Processing of Pain Information: The Limbic System

Answer 19

Emotional components of pain experienced

Question 20

Central Processing of Pain Information: Brain Stem Centers

Answer 20

Autonomic nervous system responses recruited

Question 21

What is the central processor or controller of pain?

Answer 21

The Limbic System

Question 22

Where is the The Limbic System located?

Answer 22

deep in the substance of the brain

Question 23

What is the limbic system aka?

Answer 23

“animal” or “primitive” brain

Question 24

What are the types of pain?

Answer 24

• Cutaneous
• Deep
• Visceral
• Referred

Question 25

Types of Dementia

Answer 25

Alzheimer Disease
Vascular Dementia 
Frontotemporal Dementia 
Creutzfeldt-Jakob disease 
Wernicke-Korsakoff Syndrome 
Huntington Disease