Respiratory System Flashcards
Pleural sac
Pleura and pleural cavity that enclose each side
Pleura
- Visceral: mesothelium lining surfaces of lungs
- Parietal: lines internal thoracic cavity and adheres to body wall by endothoracic fascia
A. Parts:- Costal
- Mediastinal
- Diaphragmatic
- Cervical (cupula)
Suprapleural membrane (Sibson fascia)
Fibrous extension of endothoracic fascia
- Reinforces cervical pleura
- Attaches rib 1 and transverse process C7
- Fxn: provide rigidity to superior thoracic aperture and prevents distortion w/ breathing
Pleura reflections
Abrupt lines where parts of pleura transition
1. Ex: costodiaphragmatic
Pleural cavity
Space between parietal and visceral pleura
1. Thin layer serous fluid
A. Keeps lungs in contact w/ wall
B. Lubrication
Lung gross anatomy
- Apex: superior peak, superior to 1st rib and into neck
- Base: inferior, rests on diaphragm
- Lobes: divisions created by fissures
A. Right: oblique and horizontal fissures -> 3 lobes- Superior
- Middle
- Inferior
B. Left: oblique fissure -> 2 lobes - Superior
- Inferior
- Surfaces
A. Costal
B. Diaphragmatic: concavity deeper right than left
C. Mediastinal: contain hilum of lungs - Impressions:
A. Right- Esophagus
- Azygos arch
- Superior vena cava
- Cardiac (shallow)
B. Left - Descending aorta
- Aortic arch
- Ascending aorta
- Cardiac
- Borders
A. Anterior: sharp edge where costal and mediastinal surfaces meet anterior
B. Right anterior: straight
C. Left anterior: indented by cardiac notch -> lingula
D. Posterior: rounded edge where costal and mediastinal meet posterior
E. Inferior: sharp edges between diaphragmatic, costal, and mediastinal surfaces
Bronchopulmonary segment
- Lung supplied by segmental bronchus and accompanying pulmonary artery branch
- Pulmonary vein tributaries pass intersegmentally
- Smallest functionally independent region that can be removed that can be removed w/o affecting other areas
- Right: 10
- Left: 8 or 9
Tracheobronchial tree gross anatomy
- Trachea
- Main bronchi
- Lobular (secondary) bronchi
- Segmental (tertiary) bronchi
- Bronchioles
Trachea
- Begins inferior to larynx, anterior esophagus, ends sternal angle
- C-shaped hyaline cartilage = support
- Trachealis muscle: posterior wall, connects rings, limited constriction
- Carina: cartilage ridge demarcates split into main bronchi
A. T4 level
Main bronchi
- Pass inferolaterally to lungs at hilum
- C-shaped hyaline cartilage
- Right: wider, more vertical
- Left: passes inferior aortic arch and anterior thoracic aorta
Lobular bronchi
Branches named for corresponding lobes
- Right: superior, middle, inferior
- Left: superior and inferior
Segmental bronchi
Supply corresponding segments
- Right = 10
- Left = 8-10
Bronchioles
Lack cartilage in walls 1. Conducting: 20-25 generations of branches A. End w/ terminal bronchioles B. Transport air C. No glands or alveoli 2. Respiratory: from terminal bronchiole A. Scattered alveoli in walls B. Start respiratory zone 3. Alveolar ducts arise from bronchioles -> alveolar sacs
Pulmonary circulation
- Arteries: deoxygenated blood to lungs
2. Veins: oxygenated blood to heart
Bronchial circulation
- Arteries from aorta and/or posterior intercostals
A. Oxygen and nutrients to lung tissue - Veins: drain only proximal parts of lungs
A. Rest drained by pulmonary veins
B. Right -> azygos vein
C. Left -> accessory hemiazygos or left superior intercostal vein
Lymphatic drainage
- Lungs -> hilum -> subpleural lymphatic plexus -> bronchopulmonary nodes -> intrapulmonary nodes -> bronchopulmonary nodes -> superior and inferior tracheobronchial nodes -> paratracheal nodes -> bronchomediastinal trunks
- Left -> thoracic
- Right -> right lymphatic duct
- Right lung and inferior lobe left -> right lymphatic
Lungs and visceral pleura Innervation
Nerves from pulmonary plexus
1. Sympathetic and parasympathetic efferent and visceral afferent
2. Sympathetic efferent: presynaptic from T1-T5 spinal N. Synapse in paravertebral ganglia of sympathetic trunk w/ postsynaptic -> cardiopulmonary splanchnic n. -> pulmonary plexus
A. Actions:
1. Bronchodilation: inhibits smooth muscle
2. Vasoconstriction
3. Secretory reduction
3. Parasympathetic efferent: vagus n. Enters superior thoracic aperture -> sandwiched between mediastinal pleura and fibrous pericardium
A. Presynaptic -> pulmonary plexus
B. Synapse along branches of bronchial tree
C. Actions
1. Bronchoconstriction
2. Vasodilation
3. Secretomotor
4. Visceral afferent: sensory arm of reflexes and nociception
A. Reflexive follow vagus
1. Bronchial mucosa (tactile)
2. Bronchial small muscle (stretch)
3. Interalveolar CT
4. Pulmonary arteries (baroreceptor)
5. Pulmonary veins (chemoreceptors)
B. Nociception afferents follow sympathetics
1. Input to: upper thoracic spinal n. From bronchi and bronchioles
2. Trachea follow vagus
Parietal pleura and diaphragm innervation
- Phrenic (C3-C5)
A. Somatic efferent stimulate diaphragm contraction
B. Somatic afferent stimulated from mediastinal pleura and central diaphragmatic pleura - Intercostal nerves: transmits somatic afferent from peripheral regions of diaphragmatic and costal pleura
Chest pain
- Many causes
A. Heart attack: “crushing” sub sternal pain
Rib fractures
1. 1st rib A. Rare B. Usually blunt trauma C. Often other damage (brachial plexus) 2. Middle ribs A. Most common B. Anterior to angle 3. Lower A. Can tear diaphragm -> diaphragmatic hernia 4. Painful
Flail chest
- Mult. Fractures
- Loose segment moves w/ breath
- Extremely painful
- Surgical plates/wires
Thoracotomy
Posterolateral of 5th-7th intercostal spaces important
Supernumerary ribs
- Cervical/lumbar
Ossified xiphoid process
- ~40 y/o
2. Lump -> fear tumor
Sternal fracture
- Rare
- Crush injuries
- Comminuted = several pieces
- Underlying injuries
A. 25-45% mortality
Median sternotomy
Sternal splitting
- Tumors removal
- Heart surgery
Sternal biopsy
Bone marrow needle biopsy
Complete sternal cleft
Bands don’t fuse
1. Heart can protrude
Partial sternal cleft
Manubrium and body don’t fuse
- V or U-shaped
- Usually fixed
Thoracic outlet syndrome
Obstructions of superior thoracic aperture
1. Involve upper limbs
Rib dislocation
Costal cartilage displaced from sternum
- Usually ribs 8-10
- Lump at site
Rib separation
Costochondral junction displaced
1. Ribs 3-10 -> perichondrium and periosteum tearing
Diaphragm paralysis
Individual halves can be affected
1. Seen radiographically