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MOD 4 - Pharmacology > Respiratory Drugs > Flashcards

Respiratory Drugs Flashcards

1
Q

rescue medications for asthma

A

relievers
fast acting bronchodilators

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2
Q

maintenance medications for asthma

A

controllers
prevent future attacks

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3
Q

terbutaline

A

rapid acting; short DA
B2 agonist
bronchodilator (reliever)
asthma

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4
Q

salbutamol/albuterol

A

rapid acting; short DA
B2 agonist
bronchodilator (reliever)
asthma

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5
Q

fenoterol

A

rapid acting; short DA
B2 agonist
bronchodilator (reliever)
asthma

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6
Q

formoterol

A

rapid acting; long acting DA
B2 agonist
bronchodilator (reliever & controller)
asthma

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7
Q

salmeterol

A

long acting; long DA
B2 agonist
bronchodilator (controller)
asthma

s/e: tachycardia (B1), tolerance, tremores

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8
Q

bambuterol

A

long acting; long DA
B2 agonist
bronchodilator (controller)
asthma

s/e: tachycardia (B1), tolerance, tremores

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9
Q

serevent

A

long acting; long DA
B2 agonist
bronchodilator (controller)
asthma

s/e: tachycardia (B1), tolerance, tremores

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10
Q

atropine

A

slow onset (15-20 mins)
first line relievers for COPD

anticholinergic/muscarinic
broncho dilator (reliever)
asthma

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11
Q

ipatropium

A

slow onset (15-20 mins)
first line relievers for COPD

anticholinergic/muscarinic (M3)
broncho dilator (reliever)
asthma

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12
Q

tiotropium

A

very selective
slow onset (15-20 mins)
first line relievers for COPD

anticholinergic/muscarinic (M3)
broncho dilator (reliever)
asthma

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13
Q

oxytropium

A

slow onset (15-20 mins)
first line relievers for COPD

anticholinergic/muscarinic (M3)
broncho dilator (reliever)
asthma

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14
Q

theophylline

A

narrow therapeutic index
major moa: (-) PDE (nonselective)
minor moa: (-) adenosine receptor = no ca & contraction

fatty meal = inc absorption

methylxanthine
bronchodilator (reliever & controller)
asthma

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15
Q

aminophylline

A

major moa: (-) PDE (nonselective)
minor moa: (-) adenosine receptor = no ca & contraction

methylxanthine
bronchodilator (reliever & controller)
asthma

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16
Q

doxofylline

A

major moa: (-) PDE (nonselective)
minor moa: (-) adenosine receptor = no ca & contraction

methylxanthine
bronchodilator (reliever & controller)
asthma

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17
Q

cromolyn sodium

A

chromones
indication: prophylactic, prevent bronchoconstriction

antimediator release-mast cell stabilizers
controller
asthma

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18
Q

sodium cromoglycerate

A

chromones
indication: prophylactic, prevent bronchoconstriction

antimediator release-mast cell stabilizers
controller
asthma

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19
Q

nedocromil

A

chromones
indication: prophylactic, prevent bronchoconstriction

antimediator release-mast cell stabilizers
controller
asthma

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20
Q

ketotifen

A

chromones (oral) NOT NSAID
indication: prophylactic, prevent bronchoconstriction

antimediator release-mast cell stabilizers
controller
asthma

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21
Q

zileuton

A

5-lipooxygenase enzyme inhibitor
leukotriene antagonist
controller
asthma

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22
Q

montelukast

A

LTD4 receptor inhibitor
leukotriene antagonist
controller
asthma

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23
Q

zafirlukast

A

LTD4 receptor inhibitor
leukotriene antagonist
controller
asthma

24
Q

mainstay tx for bronchial asthme

A

steroids

(-) phospholipase A2 (converts cholesterol to arachidonic acid)

(-) cytokine release by macrophage
asthma

25
budenoside
locally acting inhaled steroids controller asthma
26
bedomethasone
locally acting inhaled steroids controller asthma
27
triamcinolone
locally acting inhaled steroids controller asthma
28
fluticasone
locally acting inhaled steroids controller asthma
29
flunisolide
locally acting inhaled steroids controller asthma
30
hydrocortisone
systemic parenteral steroids (IV) controller status asthmaticus (non responsive to bronchodilators)
31
methylprednisolone
systemic parenteral steroids (IV) controller status asthmaticus (non responsive to bronchodilators)
32
prednisone
systemic oral steroids controller asthma
33
prednisolone
systemic oral steroids controller asthma
34
phenylephrine
short acting topical decongestant oral decongestant nmt 3-5 days tx decongestant (a-agonist) cough & colds preparations
35
naphazoline
intermediate acting topical decongestant nmt 3-5 days tx decongestant (a-agonist) cough & colds preparations
36
tetrahydrolozine
intermediate acting topical decongestant nmt 3-5 days tx decongestant (a-agonist) cough & colds preparations
37
oxymetazoline
long acting topical decongestant nmt 3-5 days tx decongestant (a-agonist) cough & colds preparations
38
xylometazoline
long acting topical decongestant nmt 3-5 days tx decongestant (a-agonist) cough & colds preparations
39
pseudoephedrine
oral decongestant nmt 3-5 days tx decongestant (a-agonist) cough & colds preparations
40
phenylpropanolamine
oral decongestant nmt 3-5 days tx decongestant (a-agonist) cough & colds preparations
41
levodropropizine
Levopront antitussive - peripherally acting cough & colds preparation
42
benzonatate
antitussive - peripherally acting cough & colds preparation
43
dextrometorphan
suppress cough center inc cough treshold antitussive - centrally acting cough & colds preparation
44
codeine
lolo suppress cough center inc cough treshold antitussive - centrally acting cough & colds preparation
45
noscapine
suppress cough center inc cough treshold antitussive - centrally acting cough & colds preparation
46
butamirate citrate
Sinecod lesser side effect suppress cough center inc cough treshold antitussive - centrally acting cough & colds preparation
47
guaifenesin
aka glyceryl guaiacolate Robitussin expectorant (inc respiratory tract fluid = madulas) cough & colds preparation
48
hypertonic saline
decrease viscosity (break disulfide bonds) mucolytics cough & colds preparation
49
n-acetylcysteine
Fluimucil decrease viscosity (break disulfide bonds) mucolytics cough & colds preparation
50
acetylcysteine
Mucomyst decrease viscosity (break disulfide bonds) mucolytics cough & colds preparation
51
ambroxol
Mucosolvan stimulate cilia to expel & tunaw phlegm mucoregulators cough & colds preparation
52
carbocisteine
Solmux stimulate cilia to expel & tunaw phlegm mucoregulators cough & colds preparation
53
bromhexine
Bisolvon stimulate cilia to expel & tunaw phlegm mucoregulators cough & colds preparation
54
chlorphenamine
antihistamine cough & colds preparation
55
diphenyhydramine
antihistamine cough & colds preparation
56
inhaler instructions
puff + inhale (forceful) gargle after = avoid steroids affecting normal flora (candida albicans)

MOD 4 - Pharmacology (19 decks)

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