CV Drugs - Angina/CAD Flashcards
Types: relieved by rest
stable angina
problem in supply and demand
Types: unstable
under acute coronary syndrome
ecg changes:
normal, twave inversion, ST depression
cardiac biomarkers:
low or normal CK-MB
Types: NSTEMI
under acute coronary syndrome
ecg changes:
twave inversion, ST depression
cardiac biomarkers:
high CK-MB (sign of MI - dead)
Types: STEMI
ecg changes: ST elevation
cardiac biomarkers: high troponin
nitrates: short duration
isosorbide dinitrate
sublingual
nitrates
vasodilator (inc supply)
nitrates: intermediate duration
isosorbide mononitrate
oral (for maintenance)
nitrates
vasodilator (inc supply)
nitrates: long duration
transdermal
nitrates
vasodilator (inc supply)
calcium channel blockers
dipine
vasodilator (inc supply)
cardiac depressant (dec HR & demand)
beta blockers
olol
cardiac depressant (dec HR & demand)
dec fatty acid in coronary vessels
trimetazidine
metabolism modifiers
other drugs
stable angina
nitrates (vasodilator)
CCB (vasodilator/cardiac depressant)
Bblockers (cardiac depressant)
metabolism modifiers (other)
unstable angina & NSTEMI
nitrates
dual anti-thrombotic
dual antiplatelet
anti-coagulant
ACEI/ARBS
bblockers
spironolactone
high dose statin
dual antiplatelet regimen
aspirin 80 mg x 4
clopidogrel 75 mg x 4
for unstable and NSTEMI
enoxaparin
anticoagulant
for unstable and NSTEMI
heparin
anticoagulant
for unstable and NSTEMI
prevent bara
high dose statin
for unstable and NSTEMI
remove bara
antithrombotic, antiplatelet, anticoagulant
for unstable and NSTEMI
prevent remodelling
spironolactone
ACEI/ARBS
for unstable and NSTEMI
managements of STEMI
percutaneous coronary intervention
coronary artery bypass graft
angioplasty
aka percutaneous coronary intervention (PCI) or stenting
cardiac reperfusion
for STEMI
when angioplasty is not enough
coronary bypass graft
after -> maintenance drugs
cardiac reperfusion
for STEMI
