CV Drugs - Angina/CAD Flashcards
Types: relieved by rest
stable angina
problem in supply and demand
Types: unstable
under acute coronary syndrome
ecg changes:
normal, twave inversion, ST depression
cardiac biomarkers:
low or normal CK-MB
Types: NSTEMI
under acute coronary syndrome
ecg changes:
twave inversion, ST depression
cardiac biomarkers:
high CK-MB (sign of MI - dead)
Types: STEMI
ecg changes: ST elevation
cardiac biomarkers: high troponin
nitrates: short duration
isosorbide dinitrate
sublingual
nitrates
vasodilator (inc supply)
nitrates: intermediate duration
isosorbide mononitrate
oral (for maintenance)
nitrates
vasodilator (inc supply)
nitrates: long duration
transdermal
nitrates
vasodilator (inc supply)
calcium channel blockers
dipine
vasodilator (inc supply)
cardiac depressant (dec HR & demand)
beta blockers
olol
cardiac depressant (dec HR & demand)
dec fatty acid in coronary vessels
trimetazidine
metabolism modifiers
other drugs
stable angina
nitrates (vasodilator)
CCB (vasodilator/cardiac depressant)
Bblockers (cardiac depressant)
metabolism modifiers (other)
unstable angina & NSTEMI
nitrates
dual anti-thrombotic
dual antiplatelet
anti-coagulant
ACEI/ARBS
bblockers
spironolactone
high dose statin
dual antiplatelet regimen
aspirin 80 mg x 4
clopidogrel 75 mg x 4
for unstable and NSTEMI
enoxaparin
anticoagulant
for unstable and NSTEMI
heparin
anticoagulant
for unstable and NSTEMI