CV Drugs - Angina/CAD Flashcards

1
Q

Types: relieved by rest

A

stable angina
problem in supply and demand

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2
Q

Types: unstable

A

under acute coronary syndrome

ecg changes:
normal, twave inversion, ST depression

cardiac biomarkers:
low or normal CK-MB

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3
Q

Types: NSTEMI

A

under acute coronary syndrome

ecg changes:
twave inversion, ST depression

cardiac biomarkers:
high CK-MB (sign of MI - dead)

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4
Q

Types: STEMI

A

ecg changes: ST elevation
cardiac biomarkers: high troponin

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5
Q

nitrates: short duration

A

isosorbide dinitrate
sublingual

nitrates
vasodilator (inc supply)

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6
Q

nitrates: intermediate duration

A

isosorbide mononitrate
oral (for maintenance)

nitrates
vasodilator (inc supply)

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7
Q

nitrates: long duration

A

transdermal

nitrates
vasodilator (inc supply)

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8
Q

calcium channel blockers

A

dipine
vasodilator (inc supply)
cardiac depressant (dec HR & demand)

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9
Q

beta blockers

A

olol
cardiac depressant (dec HR & demand)

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10
Q

dec fatty acid in coronary vessels

A

trimetazidine

metabolism modifiers
other drugs

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11
Q

stable angina

A

nitrates (vasodilator)
CCB (vasodilator/cardiac depressant)
Bblockers (cardiac depressant)
metabolism modifiers (other)

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12
Q

unstable angina & NSTEMI

A

nitrates
dual anti-thrombotic
dual antiplatelet
anti-coagulant
ACEI/ARBS
bblockers
spironolactone
high dose statin

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13
Q

dual antiplatelet regimen

A

aspirin 80 mg x 4
clopidogrel 75 mg x 4

for unstable and NSTEMI

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14
Q

enoxaparin

A

anticoagulant

for unstable and NSTEMI

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15
Q

heparin

A

anticoagulant

for unstable and NSTEMI

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16
Q

prevent bara

A

high dose statin

for unstable and NSTEMI

17
Q

remove bara

A

antithrombotic, antiplatelet, anticoagulant

for unstable and NSTEMI

18
Q

prevent remodelling

A

spironolactone
ACEI/ARBS

for unstable and NSTEMI

19
Q

managements of STEMI

A

percutaneous coronary intervention
coronary artery bypass graft

20
Q

angioplasty

A

aka percutaneous coronary intervention (PCI) or stenting

cardiac reperfusion
for STEMI

21
Q

when angioplasty is not enough

A

coronary bypass graft
after -> maintenance drugs

cardiac reperfusion
for STEMI