CV Drugs - HTN

Question 1

centrally acting

Answer 1

a2 agonists

clonidine, methyldopa, guanfacine, guanabenz

Question 2

peripherally acting

Answer 2

ganglionic blockers
inhibit Ne release

Question 3

non selective bblockers

Answer 3

NSTP

Question 4

selective b1 blockers

Answer 4

CINBEAM

Question 5

“pril”

Answer 5

angiotensin converting enzyme inhibitors
aka kininase II (-)

all are prodrugs except captopril & linsopril

s/e: dry cough (ACE degrade bradykinin (lung irritant)

DOC: ckd
CI: acute kidney injury, pregnancy

Question 6

“sartan”

Answer 6

angiotensin II blockers
DOC: ckd
CI: acute kidney injury, pregnancy

Question 7

“dipine”

Answer 7

dihydropyridine calcium channel blockers
vessel selective

Question 8

verapamil

Answer 8

non-dihydropyridine CCB
cardio selective

most cardio selective

Question 9

dilitiazem

Answer 9

non-dihydropyridine CCB
cardio selective

Question 10

hydralazine

Answer 10

direct vasodilator

Question 11

acetazolamide

Answer 11

carbonic anyhdrase inhibitor
diuretic (proximal convulated tubule)

doc for acute mountain sickness (alkalosis)

s/e:
dec Na, K
metabolic acidosis

Question 12

brinzolamide

Answer 12

carbonic anyhdrase inhibitor
diuretic (proximal convulated tubule)

s/e:
dec Na, K
metabolic acidosis

Question 13

dorzolamide

Answer 13

carbonic anyhdrase inhibitor
diuretic (proximal convulated tubule)

s/e:
dec Na, K
metabolic acidosis

Question 14

spironolactone

Answer 14

aldosterone antagonist
k sparing diuretics (collecting tubule & duct)

dec Na & Ca

Question 15

eprelenone

Answer 15

aldosterone antagonist
k sparing diuretics (collecting tubule & duct)

dec Na & Ca

Question 16

triamterene

Answer 16

epithileal Na channel (-)
k sparing diuretics (collecting tubule & duct)

dec Na & Ca

Question 17

amiloride

Answer 17

epithileal Na channel (-)
k sparing diuretics (collecting tubule & duct)

dec Na & Ca

Question 18

bumetanide

Answer 18

loop diuretics (thick ascending loop of henle)

s/e: hyperglycemia, hyperuricemia, hyperlipidemia

dec Na, mg, k, ca (high ceiling diuretic)
tx for pulmonary edema

Question 19

furosemide

Answer 19

loop diuretics (thick ascending loop of henle)

s/e: hyperglycemia, hyperuricemia, hyperlipidemia

dec Na, mg, k, ca (high ceiling diuretic)
tx for pulmonary edema

Question 20

torsemide

Answer 20

loop diuretics (thick ascending loop of henle)

s/e: hyperglycemia, hyperuricemia, hyperlipidemia

dec Na, mg, k, ca (high ceiling diuretic)
tx for pulmonary edema

Question 21

ethacrynic acid

Answer 21

most ototoxic

loop diuretics (thick ascending loop of henle)

s/e: hyperglycemia, hyperuricemia, hyperlipidemia

dec Na, mg, k, ca (high ceiling diuretic)
tx for pulmonary edema

Question 22

chlorthiazide

Answer 22

thiazide diuretics (distal convulated tubule)

s/e:
dec Na,K, Mg
inc Ca
hyperglycemia, hyperuricemia, hyperlipidemia

Question 23

hydrochlorothiazide

Answer 23

thiazide diuretics (distal convulated tubule)

s/e:
dec Na,K, Mg
inc Ca
hyperglycemia, hyperuricemia, hyperlipidemia

Question 24

indopamide

Answer 24

thiazide diuretics (distal convulated tubule)

s/e:
dec Na,K, Mg
inc Ca
hyperglycemia, hyperuricemia, hyperlipidemia

Question 25

chlorthalidone

Answer 25

thiazide diuretics (distal convulated tubule)

s/e:
dec Na,K, Mg
inc Ca
hyperglycemia, hyperuricemia, hyperlipidemia

Question 26

sorbitol

Answer 26

osmotic diuretic
(thin descending loop of henle)

Question 27

urea

Answer 27

osmotic diuretic
(thin descending loop of henle)

Question 28

mannitol

Answer 28

osmotic diuretic
(thin descending loop of henle)