CNS Drugs - Mood & Psychosis

Question 1

pathway: regulation of movement

Answer 1

nigrostriatal

Question 2

pathway: answer & think

Answer 2

mesolimbic

Question 3

pathway: think and happy

Answer 3

mesocortical

Question 4

pathway: endocringe

Answer 4

tuberoinfundibular

Question 5

prolactin inhibitory hormone

Answer 5

dopamine

Question 6

chlorpromazine

Answer 6

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

Question 7

fluphenazine

Answer 7

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

Question 8

haloperidol

Answer 8

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

Question 9

thioridazine

Answer 9

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

Question 10

trifluoperazine

Answer 10

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

Question 11

clozapine

Answer 11

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

Question 12

olanzapine

Answer 12

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

adjunct to Li if not enough
newer agent
bipolar drug

Question 13

quetiapine

Answer 13

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

Question 14

risperidone

Answer 14

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

Question 15

ziprasidone

Answer 15

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

Question 16

lithium

Answer 16

LiCO3
(-) release of Ne or inc reuptake

classic
bipolar drug

Question 17

carbamazepine

Answer 17

adjunct to Li if not enough

newer agent
bipolar drug

Question 18

clonazepam

Answer 18

adjunct to Li if not enough

newer agent
bipolar drug

Question 19

valproic acid

Answer 19

adjunct to Li if not enough

newer agent
bipolar drug

Question 20

DOC for mood disorders

Answer 20

SSRI

s/e: weight gain, impotence (male)

Question 21

moclobemide

Answer 21

mao a selective (-)
MAOI (mao a = degrades all catecholamines)

Question 22

phenelzine

Answer 22

mao a selective (-)
MAOI (mao a = degrades all catecholamines)

antidepressant

Question 23

isocarboxazid

Answer 23

nonselective
MAOI

antidepressant

Question 24

tranylcypramine

Answer 24

nonselective
MAOI

antidepressant

Question 25

selegeline

Answer 25

mao b selective (-)
MAOI (mao b = degrades dopa only)

antidepressant

Question 26

stimulatory

Answer 26

a2 blocker
inc sympa = in catecholamines

Question 27

amitriptylline

Answer 27

tricyclic antidepressant
non selective (inh ne, dopa, 5ht)
amino reuptake blockers

Question 28

“pramine”

Answer 28

tricyclic antidepressant
non selective (inh ne, dopa, 5ht)
amino reuptake blockers

Question 29

bupropion

Answer 29

heterocyclic antidepressant
non selective (inh ne, dopa, 5ht)
amino reuptake blockers

Question 30

mirtazapine

Answer 30

heterocyclic antidepressant
non selective (inh ne, dopa, 5ht)
amino reuptake blockers

Question 31

venlafaxin

Answer 31

serotonin-NE reuptake inhibitor
non selective
amino reuptake blockers

antidepressant

Question 32

duloxetine

Answer 32

serotonin-NE reuptake inhibitor
non selective
amino reuptake blockers

antidepressant

Question 33

“xetine”

Answer 33

serotonin selective reuptake inhibitor
amine reuptake blockers

antidepressant

Question 34

sertraline

Answer 34

serotonin selective reuptake inhibitor
amine reuptake blockers

antidepressant

Question 35

escitalopram

Answer 35

serotonin selective reuptake inhibitor
amine reuptake blockers

antidepressant