CNS Drugs - Mood & Psychosis Flashcards by rph soon

Q

pathway: regulation of movement

A

nigrostriatal

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Q

pathway: answer & think

A

mesolimbic

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Q

pathway: think and happy

A

mesocortical

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Q

pathway: endocringe

A

tuberoinfundibular

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Q

prolactin inhibitory hormone

A

dopamine

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Q

chlorpromazine

A

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

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Q

fluphenazine

A

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

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Q

haloperidol

A

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

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Q

thioridazine

A

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

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Q

trifluoperazine

A

typical antipsychotic (classic)
(-) D2 receptor
address positive symptoms

s/e: extra pyramidal symptoms, hyperprolactinemia

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Q

clozapine

A

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

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Q

olanzapine

A

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

adjunct to Li if not enough
newer agent
bipolar drug

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Q

quetiapine

A

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

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Q

risperidone

A

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

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Q

ziprasidone

A

atypical antipsychotic (newer)
serotonin-Dopa antagonist (blocks the higher one)
address both + & - symptoms

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Q

lithium

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A

LiCO3
(-) release of Ne or inc reuptake

classic
bipolar drug

Q

carbamazepine

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A

adjunct to Li if not enough

newer agent
bipolar drug

Q

clonazepam

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A

adjunct to Li if not enough

newer agent
bipolar drug

Q

valproic acid

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A

adjunct to Li if not enough

newer agent
bipolar drug

Q

DOC for mood disorders

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A

SSRI

s/e: weight gain, impotence (male)

Q

moclobemide

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A

mao a selective (-)
MAOI (mao a = degrades all catecholamines)

Q

phenelzine

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A

mao a selective (-)
MAOI (mao a = degrades all catecholamines)

antidepressant

Q

isocarboxazid

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A

nonselective
MAOI

antidepressant

Q

tranylcypramine

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A

nonselective
MAOI

antidepressant

selegeline

mao b selective (-) MAOI (mao b = degrades dopa only) antidepressant

stimulatory

a2 blocker inc sympa = in catecholamines

amitriptylline

tricyclic antidepressant non selective (inh ne, dopa, 5ht) amino reuptake blockers

"pramine"

tricyclic antidepressant non selective (inh ne, dopa, 5ht) amino reuptake blockers

bupropion

heterocyclic antidepressant non selective (inh ne, dopa, 5ht) amino reuptake blockers

mirtazapine

heterocyclic antidepressant non selective (inh ne, dopa, 5ht) amino reuptake blockers

venlafaxin

serotonin-NE reuptake inhibitor non selective amino reuptake blockers antidepressant

duloxetine

serotonin-NE reuptake inhibitor non selective amino reuptake blockers antidepressant

"xetine"

serotonin selective reuptake inhibitor amine reuptake blockers antidepressant

sertraline

serotonin selective reuptake inhibitor amine reuptake blockers antidepressant

escitalopram

serotonin selective reuptake inhibitor amine reuptake blockers antidepressant