Reproductive Endocrinology Flashcards

1
Q

What is a simple neural reflex?

A

Nerves that release simple neurotransmitters directly onto the target tissue.

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2
Q

What is a neuroendocrine reflex?

A

Needs a neurohormone to enter blood and act at a remote location.

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3
Q

What is the neural control center for repro hormones?

A

Hypothalamus/pituitary

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4
Q

What organ deposits neurohormones directly into circulation?

A

Posterior pituitary

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5
Q

What regulates GnRH?

A

Male: Tonic center
Female: Tonic and Surge centers

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6
Q

What quantity of repro hormones do you need?

A

Small quanitities

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7
Q

How long are repro hormone half-lives?

A

Short

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8
Q

Where does GnRH come from?

A

Hypothalamic nuclei

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9
Q

Where do FSH, LH and prolactin come from?

A

Anterior Pituitary

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10
Q

Where does Oxytocin come from?

A

Posterior pituitary

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11
Q

Which repro hormones are a peptide?

A

GnRH

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12
Q

Which repro hormones are a glycoprotein?

A

FSH
LH
Inhibin

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13
Q

Which repro hormones are steroids?

A

Progesterone
Testosterone
Estradiol

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14
Q

What does PGF2a do?

A

Lyses the corpus luteum

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15
Q

What does PGE2 do?

A

Relaxes the cervix

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16
Q

How do protein hormones cause their actions?

A

Bind to plasma membrane bound receptors

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17
Q

How do steroid hormones cause their actions?

A

Travel freely through the plasma membrane into the cytoplasm and bind to the specific nuclear receptors

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18
Q

What does binding of hormones result in?

A

New protein synthesis

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19
Q

What are two functions of pheromones?

A

Influence the onset of puberty

Lets the male know who is in heat

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20
Q

What 4 things affect the strength of a hormone?

A

Pattern and duration of secretion
Half-life
Receptor density (this is really important)
Receptor-hormone affinity

NOTE: We can play with receptor-hormone affinity to make synthetic hormones that bind better than the natural hormone.

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21
Q

What are3 different patterns and duration of secretion?

A

Episodic
Basal
Sustained

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22
Q

What is Episodic secretion?

A

Burst or pulse

NOTE: generally associated with hormones under nervous control.

23
Q

What is Basal secretion?

A

Secretion stays low, but fluctuates with low amplitude pulses.

24
Q

What is Sustained secretion?

A

Hormone remains elevated, but in a steady fashion for a long period.

NOTE: Steroids tend to be secreted this way.

25
Where are steroids metabolized and excreted?
Metabolized: Liver Excreted: Urine and feces
26
What organ is usually larger in high producing dairy cows?
Livers
27
Why can pregnancy tests be a urine test?
Because the protein hormones (eg. hCG) are metabolized in the liver and excreted by the kidneys.
28
What is estrus?
"Heat" or secual receptivity
29
What is estrous?
Length of the estrous cycle
30
What is an estrous cycle?
The period between one estrus and the next.
31
What is anestrus?
Not cycling
32
What does estrual mean?
Something related to estrus.
33
What 3 species are polyestrus?
Cattle Swine Rodents
34
What 4 species are seasonally polyestrus short-day breeders?
Sheep Goats Deer Elk
35
What species is seasonally polyestrus long-day breeders?
Horses
36
What 3 species are monestrus?
Dogs Wolves Bears
37
What is the follicular phase?
Follicles are dominant structure
38
What hormone is dominant during the follicular phase?
Estrogen
39
What is the luteal phase?
Corpora lutea are dominant structure.
40
What hormone is dominant during the follicular phase?
Progesterone
41
What are the 4 stages of the estrous cycle?
Proestrus Estrus Metestrus Diestrus
42
What 2 stages of the estrous cycle are in the follicular phase?
Proestrus | Estrus
43
What 2 stages of the estrous cycle are in the luteal phase
Metestrus | Diestrus
44
During what stage of the estrous cycle does estrogen secretion begin?
Proestrus
45
During what stage of the estrous cycle does estrogen secretion peak?
Estrus
46
During what stage of the estrous cycle does prostaglandin secretion being?
Metestrus
47
During what stage of the estrous cycle is progesterone secretion sustained at high levels?
Diestrus
48
Why do you need to watch progesterone levels in dogs?
Because they have a longer period of receptivity.
49
What is important to remember about diestrus in the bithc?
It is always 2 months no matter what.
50
What is important to remember about cats?
They are induced ovulators.
51
What are 5 conditions that would result in anestrus?
``` Pregnancy Lactation Seasons Stress Pathology ```
52
What are 3 factors that might cause a true anestrus?
Nutrition Stresses Pathology
53
What are 2 causes of apparent anestrus?
Failure to detect estrus | Failure to know that she is pregnant
54
What species are induced ovulators?
Llamas and Queens