Repro Hormones Flashcards
What is the biochemical classification of GnRH?
Neuropeptide
What is the biochemical classification of LH?
Glycoprotein
What is the biochemical classification of FSH?
Glycoprotein
What is the biochemical classification of prolactin?
Protein
What is the biochemical classification of oxytocin?
Neuropeptide
What is the biochemical classification of estradiol?
Steroid
What is the biochemical classification of progesterone?
Steroid
What is the biochemical classification of testosterone?
Steroid
What is the biochemical classification of inhibin?
Glycoprotein
What is the biochemical classification of activin?
Glycoprotein
What is the biochemical classification of prostaglandin F2a?
Prostaglandin (C-20 fatty acid)
What is the biochemical classification of prostaglandin E2?
Prostaglandin (C-20 fatty acid)
What is the biochemical classification of hCG?
Glycoprotein
What is the biochemical classification of eCG?
Glycoprotein
What is the biochemical classification of placental lactogen?
Protein
What is the source of GnRH?
Hypothalamic surge and tonic centers
What is the source of LH?
Anterior pituitary
What is the source of FSH?
Anterior pituitary
What is the source of prolactin?
Anterior pituitary
What is the source of oxytocin?
Synthesized by hypothalamus and CL, stored in posterior pituitary
What is the source of estradiol?
- Granulosal cells of follicle
- Sertoli cells of testis
What is the source of progesterone?
- CL
- Placenta
What is the source of testosterone?
Leydig cells (interstitial), Theca interna
What is the source of inhibin?
- Granulosa cells (female)
- Sertoli cells (male)
What is the source of activin?
- Placental cells (human female)
- Granulosa cells (female)
- Sertoli cells (male)
What is the source of prostaglandin F2a?
- Uterine endometrium (female)
- Vesicular glands (male)
What is the source of prostaglandin E2?
- Ovary
- Uterus
- Embryonic membranes
What is the source of hCG?
Trophoblast of blastocyst (chorion)
What is the source of eCG?
Chorionic girdle cells
What is the source of placental lactogen?
Placenta
What is the target tissue in the male for GnRH?
Anterior pituitary
What is the target tissue in the male for LH?
Testis (Interstitial cells of Leydig)
What is the target tissue in the male for FSH?
Testis (Sertoli cells)
What is the target tissue in the male for prolactin?
- Testis
- Brain
What is the target tissue in the male for oxytocin?
- Smooth muscle of epididymal tail
- Ductus deferens
- Ampulla
What is the target tissue in the male for estradiol?
Brain (Inhibits long bone growth)
What is the target tissue in the male for testosterone?
- Accessory sex glands
- Tunica dartos of scrotum
- Seminiferous epithelium
- Skeletal muscle
What is the target tissue in the male for inhibin?
Anterior pituitary (gonadotrophs)
What is the target tissue in the male for activin?
Anterior pituitary (gonadotrophs)
What is the target tissue in the male for prostaglandin F2a?
Epididymus
What is the target tissue in the female for GnRH?
Anterior pituitary
What is the target tissue in the female for LH?
Ovary (Theca interna and luteal cells)
What is the target tissue in the female for FSH?
Ovary (Granulosa cells)
What is the target tissue in the female for prolactin?
- Mammary cells
- CL (some species)
What is the target tissue in the female for oxytocin?
- Myometrium
- Endometrium
- Myoepithelial cells of mammary glands
What is the target tissue in the female for estradiol?
- Hypothalamus
- Entire repro tract
- Mammary gland
What is the target tissue in the female for progesterone?
- Endometrium
- Mammary gland
- Myometrium
- Hypothalamus
What is the target tissue in the female for testosterone?
- Brain
- Skeletal muscle
- Granulosa cells
What is the target tissue in the female for inhibin?
Anterior pituitary (gonadotrophs)
What is the target tissue in the female for activin?
Anterior pituitary (gonadotrophs)
What is the target tissue in the female for prostaglandin F2a?
- CL
- Myometrium
- Ovulatory follicles
What is the target tissue in the female for prostaglandin E?
- CL
- Oviduct
What is the target tissue in the female for hCG?
Ovary
What is the target tissue in the female for eCG?
Ovary
What is the target tissue in the female for placental lactogen?
Mammary gland
What is the primary action of GnRH in the male?
Release of FSH/LH from anterior pituitary
What is the primary action of LH in the male?
Stimulates testosterone production
What is the primary action of FSH in the male?
Sertoli cell function
What is the primary action of prolactin in the male?
Can induce maternal behavior
What is the primary action of oxytocin in the male?
- PGF2a synthesis
- Pre-ejaculatory moment of spermatozoa
What is the primary action of estradiol in the male?
Sexual behavior
What is the primary action of testosterone in the male?
- Anabolic growth
- Promotes spermatogenesis
- Promotes secretion of accessory sex glands
What is the primary action of inhibin in the male?
Inhibits FSH secretion
What is the primary action of activin in the male?
Inhibits FSH secretion
What is the primary action of prostaglandin F2a in the male?
- Affects activity of spermatozoa
- Causes epididymal contractions
What is the primary action of hCG in the male?
Increase growth of fetal testis
What is the primary action of GnRH in the female?
Release of FSH/LH from anterior pituitary
What is the primary action of LH in the female?
- Stimulates ovulation
- Formation of CL
- Progesterone secretion
What is the primary action of FSH in the female?
- Follicular development
- Estradiol secretion
What is the primary action of prolactin in the female?
- Lactation
- Maternal behavior
- CL function
What is the primary action of oxytocin in the female?
- Uterine motility
- Promotes uterine PGF2a synthesis
- Milk ejection
What is the primary action of estradiol in the female?
- Sexual behavior
- GnRH
- Elevated secretion of the entire tract
- Enhanced uterine motility
What is the primary action of progesterone in the female?
- Endometrial secretion
- Inhibits GnRH release
- Inhibits reproductive behavior
- Promotes maintenance of pregnancy
What is the primary action of testosterone in the female?
- Substrate for E2 synthesis
- Abnormal masculization
What is the primary action of inhibin in the female?
Inhibits FSH secretion
What is the primary action of activin in the female?
Inhibits FSH secretion
What is the primary action of prostaglandin F2a in the female?
- Luteolysis
- Promotes uterine tone and contraction
- Ovulation
What is the primary action of prostaglandin E in the female?
- Ovulation
- Stimulate CL secretion of progesterone
What is the primary action of hCG in the female?
Facilitate production of progesterone by ovary
What is the primary action of eCG in the female?
Causes formation of accessory CL
What is the primary action of placental lactogen in the female?
Mammary stimulation