Repro Hormones Flashcards

1
Q

What is the biochemical classification of GnRH?

A

Neuropeptide

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2
Q

What is the biochemical classification of LH?

A

Glycoprotein

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3
Q

What is the biochemical classification of FSH?

A

Glycoprotein

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4
Q

What is the biochemical classification of prolactin?

A

Protein

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5
Q

What is the biochemical classification of oxytocin?

A

Neuropeptide

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6
Q

What is the biochemical classification of estradiol?

A

Steroid

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7
Q

What is the biochemical classification of progesterone?

A

Steroid

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8
Q

What is the biochemical classification of testosterone?

A

Steroid

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9
Q

What is the biochemical classification of inhibin?

A

Glycoprotein

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10
Q

What is the biochemical classification of activin?

A

Glycoprotein

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11
Q

What is the biochemical classification of prostaglandin F2a?

A

Prostaglandin (C-20 fatty acid)

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12
Q

What is the biochemical classification of prostaglandin E2?

A

Prostaglandin (C-20 fatty acid)

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13
Q

What is the biochemical classification of hCG?

A

Glycoprotein

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14
Q

What is the biochemical classification of eCG?

A

Glycoprotein

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15
Q

What is the biochemical classification of placental lactogen?

A

Protein

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16
Q

What is the source of GnRH?

A

Hypothalamic surge and tonic centers

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17
Q

What is the source of LH?

A

Anterior pituitary

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18
Q

What is the source of FSH?

A

Anterior pituitary

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19
Q

What is the source of prolactin?

A

Anterior pituitary

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20
Q

What is the source of oxytocin?

A

Synthesized by hypothalamus and CL, stored in posterior pituitary

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21
Q

What is the source of estradiol?

A
  • Granulosal cells of follicle

- Sertoli cells of testis

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22
Q

What is the source of progesterone?

A
  • CL

- Placenta

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23
Q

What is the source of testosterone?

A

Leydig cells (interstitial), Theca interna

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24
Q

What is the source of inhibin?

A
  • Granulosa cells (female)

- Sertoli cells (male)

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25
Q

What is the source of activin?

A
  • Placental cells (human female)
  • Granulosa cells (female)
  • Sertoli cells (male)
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26
Q

What is the source of prostaglandin F2a?

A
  • Uterine endometrium (female)

- Vesicular glands (male)

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27
Q

What is the source of prostaglandin E2?

A
  • Ovary
  • Uterus
  • Embryonic membranes
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28
Q

What is the source of hCG?

A

Trophoblast of blastocyst (chorion)

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29
Q

What is the source of eCG?

A

Chorionic girdle cells

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30
Q

What is the source of placental lactogen?

A

Placenta

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31
Q

What is the target tissue in the male for GnRH?

A

Anterior pituitary

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32
Q

What is the target tissue in the male for LH?

A

Testis (Interstitial cells of Leydig)

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33
Q

What is the target tissue in the male for FSH?

A

Testis (Sertoli cells)

34
Q

What is the target tissue in the male for prolactin?

A
  • Testis

- Brain

35
Q

What is the target tissue in the male for oxytocin?

A
  • Smooth muscle of epididymal tail
  • Ductus deferens
  • Ampulla
36
Q

What is the target tissue in the male for estradiol?

A

Brain (Inhibits long bone growth)

37
Q

What is the target tissue in the male for testosterone?

A
  • Accessory sex glands
  • Tunica dartos of scrotum
  • Seminiferous epithelium
  • Skeletal muscle
38
Q

What is the target tissue in the male for inhibin?

A

Anterior pituitary (gonadotrophs)

39
Q

What is the target tissue in the male for activin?

A

Anterior pituitary (gonadotrophs)

40
Q

What is the target tissue in the male for prostaglandin F2a?

A

Epididymus

41
Q

What is the target tissue in the female for GnRH?

A

Anterior pituitary

42
Q

What is the target tissue in the female for LH?

A

Ovary (Theca interna and luteal cells)

43
Q

What is the target tissue in the female for FSH?

A

Ovary (Granulosa cells)

44
Q

What is the target tissue in the female for prolactin?

A
  • Mammary cells

- CL (some species)

45
Q

What is the target tissue in the female for oxytocin?

A
  • Myometrium
  • Endometrium
  • Myoepithelial cells of mammary glands
46
Q

What is the target tissue in the female for estradiol?

A
  • Hypothalamus
  • Entire repro tract
  • Mammary gland
47
Q

What is the target tissue in the female for progesterone?

A
  • Endometrium
  • Mammary gland
  • Myometrium
  • Hypothalamus
48
Q

What is the target tissue in the female for testosterone?

A
  • Brain
  • Skeletal muscle
  • Granulosa cells
49
Q

What is the target tissue in the female for inhibin?

A

Anterior pituitary (gonadotrophs)

50
Q

What is the target tissue in the female for activin?

A

Anterior pituitary (gonadotrophs)

51
Q

What is the target tissue in the female for prostaglandin F2a?

A
  • CL
  • Myometrium
  • Ovulatory follicles
52
Q

What is the target tissue in the female for prostaglandin E?

A
  • CL

- Oviduct

53
Q

What is the target tissue in the female for hCG?

A

Ovary

54
Q

What is the target tissue in the female for eCG?

A

Ovary

55
Q

What is the target tissue in the female for placental lactogen?

A

Mammary gland

56
Q

What is the primary action of GnRH in the male?

A

Release of FSH/LH from anterior pituitary

57
Q

What is the primary action of LH in the male?

A

Stimulates testosterone production

58
Q

What is the primary action of FSH in the male?

A

Sertoli cell function

59
Q

What is the primary action of prolactin in the male?

A

Can induce maternal behavior

60
Q

What is the primary action of oxytocin in the male?

A
  • PGF2a synthesis

- Pre-ejaculatory moment of spermatozoa

61
Q

What is the primary action of estradiol in the male?

A

Sexual behavior

62
Q

What is the primary action of testosterone in the male?

A
  • Anabolic growth
  • Promotes spermatogenesis
  • Promotes secretion of accessory sex glands
63
Q

What is the primary action of inhibin in the male?

A

Inhibits FSH secretion

64
Q

What is the primary action of activin in the male?

A

Inhibits FSH secretion

65
Q

What is the primary action of prostaglandin F2a in the male?

A
  • Affects activity of spermatozoa

- Causes epididymal contractions

66
Q

What is the primary action of hCG in the male?

A

Increase growth of fetal testis

67
Q

What is the primary action of GnRH in the female?

A

Release of FSH/LH from anterior pituitary

68
Q

What is the primary action of LH in the female?

A
  • Stimulates ovulation
  • Formation of CL
  • Progesterone secretion
69
Q

What is the primary action of FSH in the female?

A
  • Follicular development

- Estradiol secretion

70
Q

What is the primary action of prolactin in the female?

A
  • Lactation
  • Maternal behavior
  • CL function
71
Q

What is the primary action of oxytocin in the female?

A
  • Uterine motility
  • Promotes uterine PGF2a synthesis
  • Milk ejection
72
Q

What is the primary action of estradiol in the female?

A
  • Sexual behavior
  • GnRH
  • Elevated secretion of the entire tract
  • Enhanced uterine motility
73
Q

What is the primary action of progesterone in the female?

A
  • Endometrial secretion
  • Inhibits GnRH release
  • Inhibits reproductive behavior
  • Promotes maintenance of pregnancy
74
Q

What is the primary action of testosterone in the female?

A
  • Substrate for E2 synthesis

- Abnormal masculization

75
Q

What is the primary action of inhibin in the female?

A

Inhibits FSH secretion

76
Q

What is the primary action of activin in the female?

A

Inhibits FSH secretion

77
Q

What is the primary action of prostaglandin F2a in the female?

A
  • Luteolysis
  • Promotes uterine tone and contraction
  • Ovulation
78
Q

What is the primary action of prostaglandin E in the female?

A
  • Ovulation

- Stimulate CL secretion of progesterone

79
Q

What is the primary action of hCG in the female?

A

Facilitate production of progesterone by ovary

80
Q

What is the primary action of eCG in the female?

A

Causes formation of accessory CL

81
Q

What is the primary action of placental lactogen in the female?

A

Mammary stimulation