Canine Pharmaceuticals Flashcards
Where should fresh semen be deposited in the dog?
Cranial vagina
What is a progestin that is approved for used in breeding bitches?
Ovaban (megestrol acetate)
What species can Ovaban (megestrol acetate) not be used in?
Why?
- Cats
- Can cause diabetes mellitus
What type of dosing is required with Ovaban (megestrol acetate)?
Daily dosing
When must Ovaban (megestrol acetate) be started by in order to be effective?
Must be started in first 3 days of proestrus to be effective.
When will the next estrous cycle start after the administration of Ovaban (megestrol acetate)?
4-6 weeks earlier
Other progesterones can predispose a dog to what 2 conditions?
- Cystic endometrial hyperplasia
- Pyometra
Progesterone needs to be in what concentration or lower range to consider supplementing?
3 ng/mL
What needs to be known in order to know when to stop supplementing?
When due to whelp
What can be used later in pregnancy that allows you to still measure P4 to see if hypoluteoidism is real or not?
Regumate (Altrenogest)
If supplementing with progesterone, ideally wait until what day?
Why?
- After 45 days of pregnancy (avoid 1st trimester)
- Avoid masculinization of female pups
When should progesterone supplementation be removed?
Why?
- 2-3 days prior to due date
- Allow cervix to relax adequately
What is an androgenic compound that prevents LH release by negative feedback, thereby preventing estrus?
Mibolerone
Mibolerone is contraindicated in what species?
Why?
- Cats
- Liver toxicity
Is Mibolerone approved for use in breeding bitches?
No