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Eagle Prep Review > Repro Pharm Drills > Flashcards

Repro Pharm Drills Flashcards

1
Q

MOA of Terbutaline

A
  • B-2 Agonist
  • Used to relax the uterus; decrease contraction frequency
    (prevents premature labor)
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2
Q

What do we used Ritodrine for?

A
  • Stops premature labor
  • Smooth muscle relaxant
  • B2 agonist
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3
Q

What drug inhibits the conversion of Testosterone to DHT?

A

Finasteride
- 5 alpha reductase inhibitor
SE: gynecomastia, decreased libido

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4
Q

What drugs inhibit the conversion of testosterone to estrogen?

A

Aromatase inhibitors

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5
Q

MOA of Exemestane

A

Aromatase Inhibitor
(only one that is not an azole)

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6
Q

MOA of Degarelix

A

GnRH receptor antagonist
- treats prostate cancer
SE: hot flashes, liver toxicity

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7
Q

MOA of mifepristone

A

Progesterone receptor inhibitor

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8
Q

MOA of Misoprostol

A

PGE1 receptor analog

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9
Q

Name 3 Tocolytics (stop premature labor)

A
  • Terbutaline (B2 agonist)
  • Indomethacin (NSAIDS)
  • Nifedipine (Ca channel blockers)
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10
Q

What electrolyte imbalance is caused by oxytocin?

A

HYPOnatremia

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11
Q

MOA of Bicalutamide

A
  • inhibitor of androgen receptor
  • Used to treat prostate cancer
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12
Q

What drug is a 17 alpha hydroxylase inhibitor?

A

Ketoconazole or Spironolactone

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13
Q

MOA of anastrozole

A

Aromatase Inhibitor

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14
Q

MOA of Letrozole

A

Aromatase Inhibitors

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15
Q

MOA of Tamsulosin

A

Alpha receptor Blocker

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16
Q

Drug of Choice for a pt with Male Pattern Baldness and BPH

A
  • Finasteride (5 alpha reductase inhibitor)
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17
Q

Drug of choice for a patient with Androgenetic alopecia and HTN

A

Minoxidil

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18
Q

What is a hormone free, 99% effective contraception?

A

Copper IUD

19
Q

SE of Depo-Medroxyprogesterone (DMPA)?

A

Weight Gain

20
Q

What type of liver tumor is caused by OCPs?

A

Hepatocellular Adenoma

21
Q

MOA of Ulipristal

A

Competitive Inhibitor of progestins at progesterone receptors

22
Q

First Line of Treatment for Primary Dysmenorrhea?

A

OCPs

23
Q

SE of Tamoxifen

A
  • hot flashes
  • risk of DVTs
  • endometrial Ca.
24
Q

What is the MOA of Tamsulosin?

A

Alpha 1 Blocker (in prostate)

25
Q

MOA of Buserelin

A

GnRH analog

26
Q

In what type for pregnancy do we use Methotrexate?

A

Ectopic Pregnancy

27
Q

What is Diesthelstibestrol (DES) associated with?

A

Vaginal Clear Cell Adenocarcinoma

28
Q

Patient with breast cancer is going through chemo, an asks for a contraception, what is the best contraception for this Pt?

A

Copper IUD (no hormones)

29
Q

What are the contraindications of a Progestin-IUD?

A
  • Breast Cancer
  • Abnormal Menses
  • Uterine abnormalities
  • Active PID
30
Q

Contraindications in prescribing Ulipristal.

A

None! (unless you are pregnant and want to keep the baby)

31
Q

What are the contraindications of a Copper-IUD?

A
  • Uterine anatomy abnormalities
  • Wilson’s Disease
  • Heavy Menses
32
Q

Side Effects of Raloxifene

A
  • Increased Risk of DVTS
  • Hot flashes

NO ENDOMETRIAL CANCER RISK

33
Q

MOA of Tamoxifen on the UTERUS

A

AGONIST - at bone and uterus

ANTAGONIST - at breast

34
Q

Name all the drugs that causes gynecomastia.

A

Some - spironolactone
Funny - finasteride
Drugs - digitalis
Cause - cimetidine
Awesome - alcohol
Knockers - ketoconazole

35
Q

What are the contraindications in prescribing OCPs?

A
  • migraine with aura
  • history of breast cancer
  • DVTs
  • Smoker > 35
  • HTN
36
Q

MOA of Leuprolide

A

GnRH agonist that inhibits LH and FSH (if given continuously)

37
Q

What is the 1st line treatment for PCOS patients for infertility?

A

Clomiphene
- SERM (antagonist at estrogen receptors in hypothalamus)

38
Q

28 yr old pt who comes in with irregular menses for past six months and she is planning to conceive, physical exam, you notice there is facial hair and acne, she is 5ft tall and weight 168lbs, what is 1st line tx her symptoms?

A

Clomiphene

39
Q

Male pt comes inquiring about how to prevent gynecomastia, well built and he tells you he is taking steroids to bulk up, tx options?

A
  • STOP TAKING STEROIDS
  • also aromatase inhibitor
40
Q

How do you prevent GBS neonatal sepsis in pregnant patients?

A

Intrapartum penicillin

41
Q

What do we use Tamsulosin to treat?

A

BPH

42
Q

Which hormone is anabolic and can help in burn injury patients help recover faster?

A

testosterone

43
Q

OCPs can increase the risk of what 2 cancers?

A
  • ovarian cancer
  • endometrial cancers

Eagle Prep Review (23 decks)

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