Onc Flashcards
1
Q
RAS [blk cap]
A
- bladder cancer
- lung ca.
- kidney ca.
- colon ca.
- pancreatic ca.
BLK CP (black cap)
2
Q
N-MYC
A
- Neuroblastoma
- Small Cell Lung Carcinoma
3
Q
ERB-B1
A
Squamous Cell Lung Carcinoma
4
Q
ERB-B2
A
Breast/Ovarian Cancer
5
Q
TGF-alpha
A
- Astrocytoma
- Hepatocellular carcinoma
6
Q
BCR-ABL
A
- CML
7
Q
BRCA-1 and BRCA-2
A
- Breast Cancer
- Ovarian Cancer
8
Q
NF-1
A
- Neurofibromatosis Type 1
- Neuroblastomas
9
Q
APC
A
- FAP (familial adenomatous polyposis coli)
10
Q
DCC
A
colon cancer
11
Q
P53
A
- Li-Fraumeni syndrome
- majority of cancers
12
Q
RB
A
- retinoblastoma
13
Q
WT-1
A
- Wilm’s Tumor
14
Q
Name the Oncology Med(s)
- decreases thymidine
(inhibits nucleotide synthesis)
A
- Methotrexate
- 5-FU
15
Q
Name the Oncology Med(s)
- decreases purine synthesis
(inhibits nucleotide synthesis)
A
6-Mercaptopurine
(inhibited by xanthine oxidase)