Cell/Molecular Bio Review Flashcards
Target for Certolizumab
TNF-alpha
Target for Adalimumab
TNF-alpha
Target for Infliximab
TNF-alpha
Target for Golimumab
TNF-alpha
Target for Palivizumab
RSV F protein
Target for Bevacizumab
VEGF
Target for Trastuzumab
HER-2
Target for Eculizumab
Complement Protein - C5
Target for Ustekinumab
IL-12/IL-23
Target for Natalizumab
alpha 4 integrin
Target for Alemtuzumab
CD52
Target for Rituximab
CD20
Target for Denosumab
RANKL
Target for Abciximab
GP IIb/IIIa
Target for Omalizumab
IgE
Target for Cetuximab
EGFR
Target for Panitumumab
EGFR
Target for Pembrolizumab
PD-1
Target for Ruxolitinib
JAK1/JAK2
Target for Ipilimumab
CTLA-4
What drug(s) are used to treat
- inflammatory bowel disease
- rheumatoid arthritis
- ankylosing spondylitis
- psoriasis
Certolizumab
Adalimumab
Infliximab
Golimumab
What drug is used for prophylaxis in infants at high risk for RSV?
Palivizumab
What drug is used to treat
- Colorectal cancer
- RCC
- Non-small cell lung cancer
- proliferative diabetic retinopathy
Bevacizumab
What drug is used to treat
- breast cancer
- gastric cancer
Trastuzumab
What drug is used to treat Paroxysmal nocturnal hemoglobinuria?
Eculizumab
What drug is used to treat
- psoriasis
- psoriatic arthritis
Ustekinumab
What drug is used to treat
- Multiple Sclerosis
- Chron’s Disease
Natalizumab
What drug is used to treat
- chronic lymphoblastic leukemia
- Multiple Sclerosis
Alemtuzumab
What drug is used to treat
- B-cell non-Hodgkin lymphoma
- Chronic lymphoblastic leukemia
- RA
- ITP
- MS
Rituximab
What drug is used to treat Osteoporosis, by inhibiting osteoclast maturation?
Denosumab
What drug is used to treat Melanoma?
Ipilimumab
