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Eagle Prep Review > Cell/Molecular Bio Review > Flashcards

Cell/Molecular Bio Review Flashcards

1
Q

Target for Certolizumab

A

TNF-alpha

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2
Q

Target for Adalimumab

A

TNF-alpha

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3
Q

Target for Infliximab

A

TNF-alpha

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4
Q

Target for Golimumab

A

TNF-alpha

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5
Q

Target for Palivizumab

A

RSV F protein

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6
Q

Target for Bevacizumab

A

VEGF

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7
Q

Target for Trastuzumab

A

HER-2

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8
Q

Target for Eculizumab

A

Complement Protein - C5

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9
Q

Target for Ustekinumab

A

IL-12/IL-23

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10
Q

Target for Natalizumab

A

alpha 4 integrin

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11
Q

Target for Alemtuzumab

A

CD52

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12
Q

Target for Rituximab

A

CD20

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13
Q

Target for Denosumab

A

RANKL

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14
Q

Target for Abciximab

A

GP IIb/IIIa

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15
Q

Target for Omalizumab

A

IgE

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16
Q

Target for Cetuximab

A

EGFR

17
Q

Target for Panitumumab

A

EGFR

18
Q

Target for Pembrolizumab

A

PD-1

19
Q

Target for Ruxolitinib

A

JAK1/JAK2

20
Q

Target for Ipilimumab

A

CTLA-4

21
Q

What drug(s) are used to treat
- inflammatory bowel disease
- rheumatoid arthritis
- ankylosing spondylitis
- psoriasis

A

Certolizumab
Adalimumab
Infliximab
Golimumab

22
Q

What drug is used for prophylaxis in infants at high risk for RSV?

A

Palivizumab

23
Q

What drug is used to treat
- Colorectal cancer
- RCC
- Non-small cell lung cancer
- proliferative diabetic retinopathy

A

Bevacizumab

24
Q

What drug is used to treat
- breast cancer
- gastric cancer

A

Trastuzumab

25
Q

What drug is used to treat Paroxysmal nocturnal hemoglobinuria?

A

Eculizumab

26
Q

What drug is used to treat
- psoriasis
- psoriatic arthritis

A

Ustekinumab

27
Q

What drug is used to treat
- Multiple Sclerosis
- Chron’s Disease

A

Natalizumab

28
Q

What drug is used to treat
- chronic lymphoblastic leukemia
- Multiple Sclerosis

A

Alemtuzumab

29
Q

What drug is used to treat
- B-cell non-Hodgkin lymphoma
- Chronic lymphoblastic leukemia
- RA
- ITP
- MS

A

Rituximab

30
Q

What drug is used to treat Osteoporosis, by inhibiting osteoclast maturation?

A

Denosumab

31
Q

What drug is used to treat Melanoma?

A

Ipilimumab

Eagle Prep Review (23 decks)

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