Cell/Molecular Bio Review Flashcards

1
Q

Target for Certolizumab

A

TNF-alpha

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2
Q

Target for Adalimumab

A

TNF-alpha

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3
Q

Target for Infliximab

A

TNF-alpha

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4
Q

Target for Golimumab

A

TNF-alpha

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5
Q

Target for Palivizumab

A

RSV F protein

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6
Q

Target for Bevacizumab

A

VEGF

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7
Q

Target for Trastuzumab

A

HER-2

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8
Q

Target for Eculizumab

A

Complement Protein - C5

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9
Q

Target for Ustekinumab

A

IL-12/IL-23

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10
Q

Target for Natalizumab

A

alpha 4 integrin

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11
Q

Target for Alemtuzumab

A

CD52

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12
Q

Target for Rituximab

A

CD20

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13
Q

Target for Denosumab

A

RANKL

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14
Q

Target for Abciximab

A

GP IIb/IIIa

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15
Q

Target for Omalizumab

A

IgE

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16
Q

Target for Cetuximab

17
Q

Target for Panitumumab

18
Q

Target for Pembrolizumab

19
Q

Target for Ruxolitinib

20
Q

Target for Ipilimumab

21
Q

What drug(s) are used to treat
- inflammatory bowel disease
- rheumatoid arthritis
- ankylosing spondylitis
- psoriasis

A

Certolizumab
Adalimumab
Infliximab
Golimumab

22
Q

What drug is used for prophylaxis in infants at high risk for RSV?

A

Palivizumab

23
Q

What drug is used to treat
- Colorectal cancer
- RCC
- Non-small cell lung cancer
- proliferative diabetic retinopathy

A

Bevacizumab

24
Q

What drug is used to treat
- breast cancer
- gastric cancer

A

Trastuzumab

25
What drug is used to treat Paroxysmal nocturnal hemoglobinuria?
Eculizumab
26
What drug is used to treat - psoriasis - psoriatic arthritis
Ustekinumab
27
What drug is used to treat - Multiple Sclerosis - Chron's Disease
Natalizumab
28
What drug is used to treat - chronic lymphoblastic leukemia - Multiple Sclerosis
Alemtuzumab
29
What drug is used to treat - B-cell non-Hodgkin lymphoma - Chronic lymphoblastic leukemia - RA - ITP - MS
Rituximab
30
What drug is used to treat Osteoporosis, by inhibiting osteoclast maturation?
Denosumab
31
What drug is used to treat Melanoma?
Ipilimumab