Renal Pharm Drills Flashcards

1
Q

What type of kidney stones are caused by excess consumption of vitamin C?

A

Calcium Oxalate

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2
Q

What type of kidney stones do you see if a patient takes too much probenecid?

A

Uric Acid Calculi

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3
Q

What type of kidney stones are seen in a patient who drank anti-freeze?

A

Calcium Oxalate

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4
Q

Treatment for Calcium Oxalate Kidney Stones

A
  • Hydration
  • Hydroclorothiazide
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5
Q

SE of Furosemide

A

OH DANG
- Ototoxicity
- Hypokalemia
- Dehydration
- Allergy to Sulfa drugs
- Nephritis
- Gout

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6
Q

SE of Chorthalidone

A
  • HYPOkalemic metabolic alkalosis
  • HYPOnatremia
  • HYPERglycemia
  • HYPERlipidemia
  • HYPERuricemia
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7
Q

What do we use Furosemide for?

A
  • rapid diuresis
  • Heart Failure
  • Cirrhosis
  • Pulmonary Edema
  • HTN
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8
Q

Name the 3 Thiazide Diuretics

A
  • hydrochlorothiazide
  • chlorthalidone
  • metolazone
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9
Q

Mannitol is contraindicated in what type of patients?

A
  • Pulmonary edema
  • CHF
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10
Q

Drug of choice for metabolic alkalosis?

A

Acetazolamide (Carbonic Anhydrase Inhibitor)

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11
Q

Mechanism behind acetazolamide in the treatment of glaucoma

A

decreases production of aqueous humor

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12
Q

Which diuretics cause metabolic acidosis?

A
  • acetazolamide
  • K+ sparing
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13
Q

What diuretics cause contraction alkalosis?

A

loop and thiazide diuretics

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14
Q

What diuretics increase the risk of calcium oxalate stones?

A
  • Loops!!! (lose calcium)
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15
Q

Treatment for Urge Incontinence

A
  • Timed Voiding (bladder training)
  • Antimuscarinics
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16
Q

Treatment for Stress incontinence

A

Kegel Exercises

17
Q

Treatment for Overflow Incontinence

A
  • Catheterizations
  • Direct muscarinic agonists
18
Q

SE of ethacrynic acid

A

Ototoxicity (more than furosemide)

19
Q

MOA of Spironolactone

A

competitive antagonist at aldosterone receptor in collecting duct

20
Q

SE of Eplerone & Spironolactone

A
  • hyperkalemia
  • metabolic acidosis
21
Q

Which diuretic do we use to treat Conn’s Syndrome?

A

Spironolactone or Eplerenone

22
Q

What drugs cause acute interstitial nephritis?

A

PCNS
- penicillins
- cephalosporins
- NSAIDS
- sulfonamides

23
Q

What drugs cause Respiratory Acidosis?

A
  • opioids
  • benzodiazepines
  • barbiturates

all cause respiratory suppression

24
Q

What bipolar drug is contraindicated with giving thiazides?

A

Lithium

25
Q

Drug of Choice for Altitude Sickness/Acute Mountain Sickness?

A

Acetazolamide (CA inhibitor)