Antibiotics + Misc. Drugs Flashcards
What drugs bind to trans peptides’ e-binding protein and inhibits transpeptidase cross-linking of the peptidoglycan on the cell wall?
- Penicillins
- Cephalosporins
What drug binds to penicillin-binding protein 3 and inhibits peptidoglycan cross-linking?
- Beta - lactams (aztreonam)
What drug inhibits the cell wall peptidoglycan formation by binding to D-ala-D-ala?
Vancomycin
What drug inhibits the initiation complex by binding to 30s subunit?
- Aminoglycosides
- Tetracyclines
What drug inhibits the initiation complex by binding to 50s subunit?
Linezolid
What drug inhibits peptidyl transferase by binding to 50s Subunit?
Chloramphenicol
What drug inhibits peptide transfer by binding to 50s subunit?
Clindamycin
meaning it inhibits translocation
What drug prevents the attachment of aminoacyl tRNA?
Tetracyclines
What drug binds to 23s rRNA of the 50S subunit and inhibits protein synthesis?
Macrolides
What two antibiotics bind to cell membranes and cause cell membrane disintegrity?
- Daptomycin
- Polymyxins
Anti fungal that binds to ergosterol and causes cell membrane disintegrity?
Amphotericin B
Which antibiotic damages DNA by forming free radicals?
Metronidazole
Which antibiotic is a partial monoamine oxidase inhibitor?
Linezolid
can cause Serotonin Syndrome
Which antibiotic inhibits dihydropteroate synthase and inhibits folic acid synthesis?
Sulfonamides (SMX, Dapsone)
Which antibiotic inhibits dihydrofolate reductase?
TMP