Renal Pathology Flashcards

1
Q

Why do lipiduria and hyperlipidemia occur in nephrotic syndrome?

A

Compensate protein lose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the “lumpy bumpy” pattern in primary glomerulonephritis? In which pathology can you see it?

A
  • granular deposits of IgM, IgG, C3 through glomerulus

- APSGN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Characteristic finding in rapidly progressive glomerulonephritis

A

Crescents within bowman space

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Pathologies associated with IgA nephropathy (Berger disease)

A
  • celiac sprue

- Henoch-Schölein purpura

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which GN can rise nephrotic and nephritic syndrome, or mixed?

A

Membranoproliferative glomerulonephritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Characteristic finding in type I membranoproliferative GN at light microscopy

A

“Tram-tracking”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What suggest presence of C3 nephritic factor?

A

Type II MPGN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Most common cause of nephrotic syndrome in children

A

Minimal change disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which finding in electron microscopy do the nephrotic primary glomerulonephritis have in common?

A

Effacement of (epithelial) podocytes foot processes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Primary glomerulopathy that yields nephrotic syndrome and has a poor response to steroids

A

Focal segmental glomerulosclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Most common cause of acute renal failure in USA

A

Acute tubular necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Most common cause of nephrotic syndrome in children

A

Minimal change disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which finding in electron microscopy do the nephrotic primary glomerulonephritis have in common?

A

Effacement of (epithelial) podocytes foot processes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Primary glomerulopathy that yields nephrotic syndrome and has a poor response to steroids

A

Focal segmental glomerulosclerosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Most common cause of acute renal failure in USA

A

Acute tubular necrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Three microscopy components of Wilms tumor

A
  • metanephric blastema
  • epithelial elements (immature glomeruli, tubules)
  • stroma
17
Q

Drug cause of hemorrhagic cystitis

A

Cyclophosphamide

18
Q

How do you differentiate clinically renal cell carcinoma and transitional cell carcinoma?

A
  • RCC: hematuria, flank pain and palpable mass

- Transitional cell carcinoma (renal pelvis, ureter, bladder): painless hematuria

19
Q

Pathology associated with Kimmelstiel-Wilson lesions at light microscopy

A

Diabetic glomerulonephropathy

20
Q

Common complications of nephrotic syndrome

A
  • antithrombin III loss in urine ▶️ hypercoagulable state (ex thromboembolism)
  • loss of immunoglobulins in urine ▶️ risk of infection
  • edema ▶️ soft tissue compromise