Environment and Lifestyle Related Pathology Flashcards
1
Q
Effects of mushroom poisoning by amanita phalloides, what is the toxin?
A
- abdominal pain, vomiting, diarrhea, fulminant hepatitis, extensive liver necrosis, coma and death
- amanitin ▶️ (-) RNA polymerase
2
Q
Why is the basophylic stippling produced in lead poisoning?
A
Inhibition of pyrimidine 5’ nucleotidase
3
Q
Why is the microcytic anemia in lead poisoning produced?
A
Inhibition ferrochelatase and d-aminolevulinic acid dehydrase ▶️ ⬇️ heme synthesis