Renal Lec 2 Flashcards

1
Q

kidneys are located in __ space

A

retroperitoneal

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2
Q

retroperitoneal refers to the

A

area behind the peritoneum

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3
Q

kidneys are in __ position

A

posterior

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4
Q

associated organs of kidneys

A
  • ureter
  • bladder
  • urethra
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5
Q

ureter (def.)

A

tube that carries urine from kidney to bladder (there are 2)

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6
Q

bladder (def.)

A

hollow organ in lower abdomen that stores urine

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7
Q

urethra

A

tube that carries urine from bladder to expel it

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8
Q

micturition

A

the action of urinating

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9
Q

2 sections of kidney

A
  • outer cortex

- inner medulla

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10
Q

the functional unit of kidney is

A

nephron

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11
Q

number of nephron in each kidney

A

-roughly one million

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12
Q

two parts of the nephron

A
  • renal corpuscle

- renal tubule

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13
Q

age you age, the number of nephrons

A

decreases

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14
Q

renal corpuscle is

A

the filtration unit of nephrons

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15
Q

renal corpuscle contains

A
  • glomerulus

- bowman’s capsule

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16
Q

structure of nephron

A
  • renal corpuscle
  • proximal convoluted tubule
  • loop of henle (descending limb)
  • loop of henle (ascending limb)
  • distal convoluted tubule
  • collecting duct
17
Q

loop of henle is a ___ loop

A

hairpin

18
Q

the specificity of each section of the tubule is due to

A

the epithelial cells that vary in structure and function based on the task it has to perform

19
Q

which is more convoluted? distal or proximal

A

proximal convoluted tubule

20
Q

afferent arteriole

A

-blood vessel into glomerulus

21
Q

efferent arteriole

A

-blood vessel out of glomerulus

22
Q

layers of renal corpuscle

A
  • podocytes
  • bowman’s space
  • outer wall of bowman’s capsule
23
Q

stage 1 - renal corpuscle development

A

-nephrons are first blind-ended tubules with a single layer of epithelium

24
Q

stage 2 - renal corpuscle development

A
  • tuft of capillaries penetrate end of tubules to create a basal lamina between endothelial cells of capillaries and epithelium
  • epithelial cell layer differentiates into partial (outer) and visceral (inner) layer
25
Q

stage 3 - renal corpuscle development

A
  • visceral layer becomes podocytes

- parietal layer becomes flattened bowman’s capsule wall

26
Q

anatomy of renal corpuscle (glomerular capillary)

A
  • fenestrated endothelial layer
  • basement membrane
  • podocytes with filtration slits
27
Q

where are renal corpuscles found?

A

all renal corpuscles are found in the cortex

28
Q

basic functions of nephrons

A
  • filtration
  • reabsorption
  • secretion
29
Q

two types of nephrons

A
  • cortical (85%)

- juxtamedullary (15%)

30
Q

cortical nephrons do

A

basic functions of nephrons

31
Q

juxtamedullary nephrons do

A
  • basic functions of nephrons

- regulate the concentration of urine by the absorption of water

32
Q

cortical nephrons characteristics (4)

A
  • corpuscle is higher up in the cortex
  • short loop of henle that doesn’t penetrate medulla deeply
  • small glomerulus
  • no vasa recta only peritubular capillaries
33
Q

juxtamedullary nephrons characteristics (4)

A
  • corpuscle is lower up in the cortex, close to medulla
  • long loop of henle that penetrates medulla deeply
  • large glomerulus
  • vasa recta only , no peritubular capillaries
34
Q

blood supply to kidney

A

20% of cardiac output, highly vascular organ

35
Q

three types of capillaries

A
  • glomerular
  • peritubular
  • vasa recta
36
Q

peritubular capillaries are around __ and supplied by ___

A
  • proximal + distal tubules

- efferent arteriole

37
Q

peritubular capillaries is mostly in (type of nephrons)

A

cortical nephrons

38
Q

vasa recta capillaries are in (type of nephrons)

A

juxtamedullary nephrons

39
Q

vasa recta lie

A

parallel to loop of henle