Quiz 4 Flashcards
Histology
Three basic parts of human cells
Plasma membrane, cytoplasm, and nucleus
Cytoskeleton
Elaborate series of rods throughout cytosol
Microfilaments
- Made of actin
- Involved in cell motility, change in shape, endocytosis and exocytosis
Intermediate filaments
- Keratins, vimentin, desmin
- Resist pulling forces/mechanical strength for the cell and attach desmosomes
Microtubules
- Made of tubulin
- Determine overall shape of cell and distribution of organelles
Cell cycle
Defines changes from formation of the cell until it reproduces
Interphase
- Period from cell formation to cell division
- Nuclear material= chromatin
- Subphases: G0, G1, S, and G2
G0 Phase
Gap phase in cells that permanently cease dividing
G1 Phase
Vigorous growth and metabolism
S (synthetic) phase
DNA replication
G2 Phase
Preparation for division
Mitotic Phase
Two distinct events:
- Mitosis (Prophase, metaphase, anaphase, and telophase)
- Cytokinesis
Cytokinesis
Division of cytoplasm by cleavage furrow
Tissue
Group of cells similar in structure and function
4 types of tissues
- Epithelial
- Connective
- Muscle
- Nervous
2 types of epithelial tissue
- Covering and lining epithelia (external and internal)
- Glandular epithelia (secretory tissue in glands)
Characteristics of epithelial tissue
1) Cells have polarity
2) Closely packed cells
3) Supported by reticular lamina
4) Avascular (rely on diffusion for O2)
5) Innervated
6) High rate of regeneration (can cause cancer)
Apical (epithelial)
- Upper membrane
- Can have microvilli (intestinal lining) or cilia (trachea)
Basal (epithelial)
Lower membrane; attached to surfaces
Basal lamina
- Made by epithelium
- Noncellular, glycoprotein, collagen
Basement membrane
Reticular lamina and basal lamina together
1 layer of epithelial cells
Simple epithelium
Multiple layers of epithelial cells
Stratified epithelium
Squamous cells
Flat cells; flat nuclei
Cuboidal cells
Cube shape; round nuclei
Columnar cells
Column shape; typically oblong nuclei near basal side
Glandular epithelia
Makes and secretes an aqueous fluid, can be lipid or steroid rich in nature
Endocrine glands
- Ductless glands (secrete into blood)
- Secrete hormones
- E.g. ovaries, testes, pituitary