Quiz 3 Flashcards
Afferent
Movement of signals toward the CNS
Efferent
Movement of signals away from CNS
Central nervous System (CNS
- Brain and spinal cord
- Integrative and control centers
- Developed from neural tube
Peripheral nervous system (PNS)
- Cranial nerves and spinal nerves, visceral nerves and plexuses, enteric nervous system (of the GI
- Communication lines between the CNS and the rest of the body
- Develop from neural crest cells
Paired Cranial and Spinal Nerves
- 12 paired cranial nerves
- 8 paired cervical nerves
- 12 paired thoracic nerves
- 5 paired lumbar nerves
- 5 paired saccral nerves
- 1 pair of coccygeal nerves
Meninges
- membrane that covers and protects CNS
- protect blood vessels and enclose venous sinuses
- contain CSF
- form partitions in the skull
- form sinuses for return of CSF to venous system
Dura mater
- Most external meningeal layer of brain
- Form partitions and venous structures
- Continues as epineurium on spinal nerve (no CSF leak)
- Originates from mesoderm
Endosteal/periosteal
Outer layer of dura mater of brain
Meningeal
- Inner layer of dura mater of brain
- Also covers spinal cord
Extradural space
Upper potential space in dura
Subdural space
Lower potential space in dura
Arachnoid Mater
- Middle meningeal layer of brain (looks like spider web)
- Avascular; is not attached to dura
- Projections through subarachnoid space (CSF and vessels here) toward pia mater become continuous with pia mater
- Only found over surface of brain and in longitudinal fissure
- Originates from neural crest (cranially) and mesoderm (caudally)
Pia Mater
- Attached to CNS tissue; very delicate
- Most internal meningeal later of brain
- Denticulate ligament in spinal cord
- Originates from neural crest (cranially) and mesoderm (caudally)
Leptomeninges
Arachnoid and pia mater
Sinus
Open space; brings CSF back into circulation
Denticulate ligament
Comes off pia mater and attaches to dura to hold spine in place
Falx cerebri
Divides cerebral hemispheres
Falx cerebelli
Divide cerebellar hemispheres
Tentorium cerebelli
Separate cerebrum and cerebellum
Diaphragma sellae
- Covers the sella turcica, infundibulum passes through it
- Over the pituitary gland
Dural sinuses
Openings in two layers of dura mater within partitions
Superior sagittal sinus
Runs along hemisphere midline of brain; above inferior sagittal sinus
Arachnoid granulations
Allow CSF to enter dural sinuses and ultimately venous circulation via the internal jugular vein
Confluence of sinuses
Connecting point of the superior sagittal sinus, straight sinus, and occipital sinus. It is found deep to the occipital protuberance of the skull.
Straight sinus
The straight sinus receives blood from the superior cerebellar veins and inferior sagittal sinus and drains into the confluence of sinuses.
Transverse sinus
Allow blood to drain from the back of the head. They run laterally in a groove along the interior surface of the occipital bone
Great cerebral vein
One of the large blood vessels in the skull draining the cerebrum of the brain
Sigmoid sinus
The sigmoid sinus is a dural venous sinus situated within the dura mater. The sigmoid sinus receives blood from the transverse sinuses
Inferior sagittal sinus
An area beneath the brain which allows blood to drain outwards posteriorly from the center of the head. It drains (from the center of the brain) to the straight sinus (at the back of the head), which connects to the transverse sinuses. Meets with great cerebral vain to form straight sinus.
Cavernous sinus
A true dural venous sinus (not a venous plexus) creating a cavity called the lateral sellar compartment bordered by the temporal bone of the skull and the sphenoid bone, lateral to the sella turcica.
Neural tube
- CNS
- Brain, spinal cord
- Cells: neurons and glia
Neural crest cells
- PNS
- Nerves, ganglia, some glia cells
- Andrenal gland medulla
Neurulation
Formation of the neural tube from the neural plate
1) Neural plate (day 19)
2) neural folds
3) Fusion of neural folds at cervical region
4) neural tube is formed-> cranial and caudal neuropores open (day 23)
5) Neuropores close and NCC begin migration (day 25)
6) Neural tube flexures develop (day 28)
Fusion of neural folds begins in ____ then moves _____ and _____.
cervical region; cranially and caudally
Anterior and posterior neuropores
Communicate/connect to amniotic cavity
Primary brain vesicle
Forebrain (prosencephalon), midbrain, hindbrain (Rhombencephalon)
Telencephalon
- Secondary brain vesicle of forebrain
- Generates cerebrum: cerebral hemispheres (cortex, white matter, basal nuclei)
- Lateral ventricles
Diencephalon
- Secondary brain vesicle of forebrain
- Generates diencephalon (thalamus, hypothalamus, epithalamus), retina
- Third ventricle