Quiz 1 Flashcards
Embryonic Period
Highest risk of birth defects; 3-8 weeks gestation
Teratology
Study of birth defects
Malformation
Alteration, graded deletion of a body part during its formation; e.g. phocomelia caused by thalidomide
Syndrome
A group of anomalies occurring together with a common cause; e.g. Fetal Alcohol Syndrome
Fetal Alcohol Syndrome (FAS)
Structural defects, growth deficiency, and intellectual disability; Indistinct philtrum, thin upper lip, depressed nasal bridge, short nose, flat midface
Association
Nonrandom appearance of two or more anomalies that occur together more frequently than by chance with an unknown cause
Disruption
Alteration of an already formed structure; destructive process; e.g. Amniotic band disruptions (cleft lip, toe and finger amputations)
Deformation
Mechanical force molds fetus; e.g. club feet and abnormal limb position (oligohydraminos: insufficient amniotic fluid)
Teratogen
A substance/factor that causes birth defects
Principles of teratology
- Susceptibility depends on genotype of conceptus and environmental interaction
- Developmental stage
- Manifestation depends on dose and duration of exposure
- Teratogens have specific mechanisms
- Manifestations= death, malformation, growth reduction, and functional disorder
Ectoderm (blue)
skin, CNS, eyes, internal ear, neural crest cells (PNS, bones and connective tissue of the face and part of the skull)
Mesoderm (red)
bones, connective tissue, urogenital system, cardiovascular system, and notochord
Endoderm (yellow)
gut and gut derivatives epithelium (liver, pancreas, lungs, etc.)
11 Biological Systems
- Integument (skin)
- Circulatory (cardiac + lymphatic)
- Urinary
- Respiratory
- Skeletal
- Endocrine
- Immune
- Nervous
- Muscular
- Reproductive
- Digestive/GI
Anatomical position
- Face forward: head and feet anteriorly facing, neutral expression, closed mouth
- Feet parallel
- Arms at side with palms facing anterior (fingers together)
Anterior/ventral
Front
Posterior/dorsal
Back
Medial
Toward midline
Intermediate
Inbetween
Lateral
Away from midline
Superior/cranial
Toward head
Inferior/caudal
Toward feet
Superficial/external
Toward the body surface
Deep/internal
Away from the body surface
Proximal
Closer to the point of connection to the body
Distal
Further away from the point of connection to the body
Sagittal Plane
Divides body into left and right directions
Transverse Plane
Divides body into superior and inferior positions
Coronal (frontal) plane
Divides body inter anterior and posterior portions
Longitudinal Section
Lengthwise section
Cross (transverse) section
Width of segment
Oblique section
Cross section at an angle
Palpation
To examine or explore the body by touch
Dorsal body cavity
Cranial and vertebral cavities
Ventral body cavity
Thoracic: mediastinum and pleural
Abdominopelvic: abdominal and pelvic
Cephalic Region
Face
Frontal
Forehead/top of nose
Orbital
Eyes
Nasal
Nose
Oral
Mouth
Mental
Chin
Cervical region
Neck
Thoracic region
Chest