Pyelonephritis Flashcards

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1
Q

What is pyelonephritis?

A

Ascending bacterial infection in the upper urinary tract

- Kidneys, ureters, renal pelvis, parenchyma

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2
Q

Is pyelonephritis acute or chronic?

A

Both

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3
Q

What 2 microbes are usually the cause of pyelonephritis? What route do they enter the urinary tract via?

A
  • E. coli via the urethra

- Staphylococcus aureus via the blood

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4
Q

What are the risks for pyelonephritis?

A
  • Compromised immune response
  • Catheterization
  • Urine stasis and reflux
  • Diabetes mellitus
    • Increased glucose can be utilized by the bacteria
    • Causes vascular damage
      - Compromised circulation, IR, removal of waste
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5
Q

Quick overview of the patho of pyelonephritis:

A

Bacteria enter urethra -> ascend to bladder -> then ureter -> kidneys -> infct -> inflm -> fibrosis + inflm damage -> decreased renal fx

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6
Q

Quick overview of the patho of chronic pyelonephritis:

A

Same patho as acute pyelonephritis -> persistent inflm -> progressive renal damage -> renal failure

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7
Q

What are the mnfts of pyelonephritis?

A
  • Fever
  • Pyuria
    • Pus in urine
  • Lower back pain
  • Dysuria
  • Increased frequency
  • Urgency
  • Hypervolema
    • HTN if chronic
    • Edema
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8
Q

What is the Tx for pyelonephritis?

A
  • Abx (10-14 days)
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