Ovarian Cancer Flashcards
1
Q
Ovarian cancer is the worst reproductive cancer in women.
A
- There is no screening test
- It is difficult to diagnose
- 75% chance of already having mets at diagnosis
2
Q
What are some risks/Et of ovarian cancer?
A
- Aging (~65 to 85yrs)
- Some inherited forms
- Familial risk
- Infertility ??
- Nulliparity ??
3
Q
T or F:
If ovarian cancer has been inherited, this would be due to an autosomal recessive trait
A
F, autosomal dominant
4
Q
What are the 3 diverse forms of ovarian cancer?
A
- Germ cells (oocyte)
- Stromal cells (connective tissue cells)
- Epithelial cells (~90%)
5
Q
The progression of ovarian cancer is silent, where would you anticipate it might extend to? Could you expect seeding to occur?
A
- Extension: Fallopian tubes, uterus, other ovary
- Seeding: Liver, bowel, other structures within the
abdominal body cavity
6
Q
What might trigger the 1st detection of ovarian cancer?
A
- Abdominal distention due to the inflation of the ovary
- Pressure on adjacent organs from the affect
ovary/structures may cause abdominal discomfort
7
Q
What are mnfts of ovarian cancer?
A
- Early: non-specific GI mnfts
- Pelvic mass (1st, but late finding)
- Abdominal distention
- Urinary and bowel obstruction
- Ascites and dyspnea
- Pain
8
Q
By the time abdominal distention, urinary and bowel obstruction, and ascites and dyspnea have become mnfts of ovarian cancer, what is likely to have happened?
A
Metastasis
9
Q
What are the Dx for ovarian cancer?
A
- Transvaginal US
- Laparoscopy
- CA antigen 125 ??
- Not used for screening because it may be present
physiologically, levels fluctuate - Used to monitor and in high risk for ovarian cancer
- Not used for screening because it may be present
10
Q
What is used to treat ovarian cancer?
A
- Aggressive approach
- Radical surgery
- Remove ovaries, uterus, tubes, and omentum
- Chemo following surgery
- Repeat laparoscopy (6-12 months later)
