Potassium sparing diuretics Flashcards
1
Q
What are the generic and brand names for potassium sparing diuretics?
A
• Spironolactone (Aldactone)
2
Q
What is the method of action of potassium sparing diuretics?
A
- Competitive inhibitor of aldosterone
- Acts in the distil tubule of the nephron
- Na and K is secreted and water is lost
3
Q
What are the indication for potassium sparing diuretics?
A
• Treatment for hypokalaemia caused by loop or thiazide diuretic therapy
4
Q
What are the contraindications for potassium sparing diuretics?
A
- Hyperkalaemia
* Renal insufficiency
5
Q
What are the side effects of potassium sparing diuretics?
A
- Gynaecomastia/impotence/breast tenderness/increased hair growth
- Electrolyte disturbances
- Hypotension/dizziness
- GI upset
6
Q
What drug interactions occur with potassium sparing diuretics?
A
- Potassium supplements/other potassium sparing drugs
- Digoxin – dose may need altering
- Lithium – dose may need altering
7
Q
How are potassium sparing drugs eliminated?
A
- Urine
* Faeces
8
Q
What patient information should be given to the patient taking potassium sparing drugs?
A
• Urinary frequency will increase
