Alpha blockers Flashcards
1
Q
What are the generic and brand names of alpha blockers?
A
- Doxazosin (Cardozin)
* Tamsulosin (Flomax)
2
Q
What is the method of action of alpha blockers?
A
- Most are highly selective for α-adrenoceptor
- α-adrenoceptor are found in smooth muscle
- Blocking receptors causes vasodilation and ↓ resistance to bladder outflow
3
Q
What are the indications for alpha blockers?
A
- First line for improvement of BHP
* Add on treatment in resistant hypertension
4
Q
What are the contraindications for alpha blockers?
A
• Postural hypotension
5
Q
What are the side effects of alpha blockers?
A
- Postural hypotension
- Dizziness
- Syncope
6
Q
What drugs interact with alpha blockers?
A
• Antihypertensives – be cautious of dropping the blood pressure too much
7
Q
What organ eliminates alpha blockers?
A
Kidney
8
Q
What information should be given to a patient taking alpha blockers?
A
• Best to be taken at bedtime