Pituatary diseease

Question 1

what is hyper sectino of gh

Answer 1

acromeglay or gigantism if before epitpseal plates seal

Question 2

what is hypersection of acth

Answer 2

cushings

Question 3

what is hypersection of prolactin

Answer 3

hyperprolactinemae

Question 4

what is hyposection of main cause

Answer 4

tumoru in pitutaary

Question 5

what are teh soft tissues overgrowth signs of acromegaly

Answer 5

spade like hands
wide feet
coarse facial features
thick lips and tounge
carpal tunnel syndome
sweatting

Question 6

complacation of acromegaly

Answer 6

headach, chiasmal compression, diabetes mellitus, hypertieon
cardiomyotphy
sleepapnes
colon polyps

Question 7

how si teh diagnoss of acromglay made

Answer 7

gh - and if it can be supersed by insulin- through inclrus glucose
vision changes
igf 1 as it has a longer half life than gh
mri for pituatar ademnoa

Question 8

acromelgy

Answer 8

hyposection of gh from anteiroer pituatary

Question 9

type of cacner of acromeglay

Answer 9

pitutary adenoma

Question 10

non pituary cause of acromeglay

Answer 10

other cancers such as lung or pancreastic stimuar gsrh

Question 11

treatment for acromegaly surgery

Answer 11

removal of pituary tumour through trans spenoid surgery
radiothary
hormones to stop growth of tumour

Question 12

medical treatment ofr acromegaly

Answer 12

Pegvisomant is a growth hormone receptor antagonist given daily by a subcutaneous injection
Somatostatin analogues (e.g., octreotide) block growth hormone release
Dopamine agonists (e.g., bromocriptine) block growth hormone release

Question 13

cause of cushing

Answer 13

excess cortisol

Question 14

effet of cushings

Answer 14

tissue breakdown,, sodium retieion inuslin antagonism (diabetes)

Question 15

signs of cushigh

Answer 15

skin atrpoy
spontaneous purpura
proxial myopthy
osteoproriss
growth arrest in childrne
pink striea
facila mooning
odema

Question 16

achtm dependt cushing syndome

Answer 16

pittuar tumoru - cushings disease
ecotpic acht section form lung cancer

Question 17

acth indepent cushings

Answer 17

adrenal tumoure
corticosterid treatmetn

Question 18

causes of hyperproalciam

Answer 18

pregnancy, laction and stress
pharmalogical - da depleting and da antagonist
pathological 0 primary hypothyroidsm , pituatary lesions

Question 19

symptons of hyperprolacinemae in women

Answer 19

galactorrhoea
menstural irregulatiry
inferitly

Question 20

symptoms of hyperprolactinaemia in men

Answer 20

galactorrhoea, impotence, visual field abnormalities , headache, extraocular muscle weakness, anterior pituitary malfunction

Question 21

drugs that cuase hyperprolaciname

Answer 21

da depleting agents
dopamine antagois - neuroleptics, antiemetics
osetrogen
some antidepressants

Question 22

clincal features in adults of hypopituitarism

Answer 22

tiredness, weight gain, depresssion, reduced libo, impotenece, menstration probel, skin pallar, reduced body hair

Question 23

clicnal fearut of hypotitipicm children

Answer 23

reduced linar growth, delayed puberty

Question 24

effet of acp water deperation test

Answer 24

depreve wtaett for peroid of tiem , then gi e sympth adh to shwo that it is a probel with low adh

Question 25

causes of diabetes inspitus

Answer 25

lack of ach or lack of respose to adh

Question 26

what type of diabetes inspitu is lack of adh

Answer 26

central

Question 27

what type of diabetes inspiitus is lack of respone to adh

Answer 27

neprogenic

Question 28

Polyuria

Answer 28

excessive ammont of urine

Question 29

Polydipsia

Answer 29

excessive thrist

Question 30

what is sympootns of diabets inspigptus

Answer 30

polydispia and polyruia

Question 31

what is priamry polydispia

Answer 31

due to the paiten dirinkin too much water and not due to diabetes

Question 32

cause of central diabets inspipitus

Answer 32

Brain tumours
Brain injury
Brain surgery
Brain infections (e.g., meningitis or encephalitis)
Genetic mutations in the ADH gene (autosomal dominant inheritance)
Wolfram syndrome (a genetic condition also causing optic atrophy, deafness and diabetes mellitus)

Question 33

cuase of peripharl diabetse insipidus

Answer 33

Medications, particularly lithium (used in bipolar affective disorder)
Genetic mutations in the ADH receptor gene (X-linked recessive inheritance)
Hypercalcaemia (high calcium)
Hypokalaemia (low potassium)
Kidney diseases (e.g., polycystic kidney disease)

Question 34

effect of piamry polydispa on water withdra

Answer 34

will casue urien osmoarl to be high thus adh will not need to be given

Question 35

effect of stomaot stain analgine ia cacmeo

Answer 35

impoef sties oergowth , sleep apena
fix gh and igf levles
cuase brain tumou to shrink

Question 36

adverse effects of stoamtostopin analge

Answer 36

nausea, cramps, dirrhoea, flatulence, cholestol gallstones, slow relase peperation with montly im/sc injection

Question 37

what are example somatostatin

Answer 37

octreotide
lanreotide

Question 38

what is exajme of modifed analag gorwth hormone

Answer 38

pegvisomant

Question 39

what is micropolacioma

Answer 39

where the pituar gland is les than 10 but cuase prolaciaom side effects

Question 40

treatmetn for micorpolaioma

Answer 40

dopamien agonisits e.g. cabergoline

Question 41

treatmetn of macropolactinoma

Answer 41

dopamine agoniss

Question 42

time to treat prolacinoma with dopane agaos

Answer 42

normally a few days