Pathology of diabtes Flashcards
part of pancres taht secree endocrine
islets of langerhans
what percent of isltes of langerhns is beta cells
2/3
what molcue is assoced with t1d
molcues that help t cells reconges self form non self e.. human leukocyte antigen molcues
triggers for t1d
chemicals
bacteria in the gut
viral infection
enviromental factor t2d
increased vicarl fat
increased free fatty acids in the blood
decreased insulin receptor sensitivty
main factor that effect t2d
gene
how is atherosicler accerlaed in dibtes
glucose attaches to ldl
thus stopping ldl from binding to receporr on liver
thus it is not removed by liver cells increasing the amount of LDL in the blood
thus leading to atheroslcleris
where is the molcues such as plaam protein and ct stoend in blood vessl in diabtes
they are stored in teh subendothial space, and can’t find the way out
thus thinkgni basal lamina