Pathology of endocrine disease Flashcards
what does a adenohypophhysis secret
acth, tsh, gh, prolatin and fsh, oh
wher is an adenohypophs found
in the antiero pituary
where is a neurohyposthso found
in th epostuor pituary
how doe a neurohypos form
down growht of the postioer pituratyr
what does a neurohyposys sectre
adh, oxytocin
most common cause of pituatyr hyerfuiton
pituary adenaom
what is the cuase of pituar doem
MOST OCMLY SPORATID BUT CNA BE ASSOCATED WITH MEN 1 GENE
effect of pituary adenaom
if fuciton - will cuas hormen exess e.g. galactorreha, menaution disor if prolaio
gh seciton - acromely
acth - cugiongs
non fucniton - can cuase viusl fil aboma nd raised icp
cause of pituary hypofuction
compression by tumor such as craniophyngioma
tramua
infectino - such as tb adnd sarcoidso
grave disase cuase
anti tsh recort antiboids
cause of hypo thyodism
hashiomos
lartorngei
iodine defin
congeital
types of thyrodi gand cancer
follicular adneoama
caronma - makes up 5% of cancers
- papllary - 75%
Folliucaor - 10%
medullary / lymphoa - 5%
anaplatic 5%
what is papilary cariona assoiced with
braf muation and ionzing radiation
what is medullar carcinoma assoicaed with
mend 2a, men2b, famialry fmtc
treatment for thyrodi cancoma
surgery, radioactive iodine, external raidothery, chemotharym