Physiology: pain Flashcards

1
Q

Physiology: pain

pain resulting from a stimulus that usually does not provoke pain

A

allodynia

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2
Q

Physiology: pain

Following joint or muscle inflammation __________ of primary afferent fibers occurs

A

sensitization

increase in spontaneous activity โ†’ increase response to the same noxious stimulus

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3
Q

Physiology: pain

substances are released from inflammatory cells that can activate or sensitize primary afferent fibers

A
  • Serotonin: causes pain in humans, released from platelets.
  • Bradykinin: released from plasma after tissue damage.
  • Prostaglandins
  • Cytokines
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4
Q

Physiology: pain

gate control theory

A

Activation of large diameter afferent fibers by pressure, proprioception, touch or vibration inhibits transmission of pain by small afferent fibers

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5
Q

Physiology: pain

types of pain

A

mechanical, chemical (inflammatory), neurogenic/psychological (chronic low back pain)

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