Adult neuro: Guillain-Barre Syndrome

Question 1

Adult Neuro: GBS

what is Guillain-Barre syndrome?

Answer 1

rapid onset of bilateral muscle flaccid weakness and sensory impairments caused by the immune system damaging/demyelinating of peripheral nerves. Can be viral or Bacterial.

Question 2

Adult Neuro: GBS

key objective examination in GBS

Answer 2

• History (pattern, sequence of symptoms)
• Motor function: AROM/PROM/MMT; cranial nerves; respiratory; balance; posture; functional assessment
• Sensory: dermatomes; type of sensory loss; pain
• Autonomic changes: vitals; B & B function
• Outcomes measures: GBS Disability Scale

Question 3

Adult Neuro: GBS

GBS exercise precautions

Answer 3

excessive exercise during early reinnervation can lead to further damage rather than to the usual exercise-induced muscle hypertrophy
Avoid muscle fatigue/overuse

Question 4

Adult Neuro: GBS

phases of GBS

Answer 4

1. Acute <4 weeks (GBS should not progress after 4 weeks)
2. Subacute 4-8 weeks
3. Chronic > 8 weeks

Question 5

Adult Neuro: GBS

GBS lab tests include CSF (protein levels and WBC count) and nerve conduction velocity. What results would you expect in these lab tests?

Answer 5

• CSF: elevated protein (because of myelin is broken down), and normal WBC
• Abnormal NCV: slower

Question 6

Adult Neuro: GBS

reflex testing results in GBS

Answer 6

decreased or absent