Phosphodiesterase Inhibitors

Question 1

Common Facts

Answer 1

Commonly used to treat: ED (erectile dysfunction)
Common adverse reaction: flushing, dizziness, headache, visual effects (light sensitivity, loss of vision), life threatening drop in blood pressure if taken with nitrates, use with caution in men also taking alpha antagonists, anti-fungals, macrolide antibiotics
Common auxiliary labels: avoid grapefruit, avoid nitrates

Question 2

Mechanism of Action

Answer 2

Relax smooth muscle and blood vessels controlling penile enlargement
Increase nitric oxide (NO) levels

Question 3

Cialis

Answer 3

Generic name: tadalafil

Tablets: 2.5mg, 5mg, 10mg, 20mg

Question 4

Levitra

Answer 4

Generic name: Vardenafil

Tablets: 5mg, 10mg, 20mg