Bisphosphonate

Question 1

Common Facts

Answer 1

Common ending: -dronate
Commonly used to treat: osteoporosis
Common adverse reaction: painful swallowing, heartburn, N/V/D (nausea/vomiting/diarrhea), can cause damage to esophagus
Common auxiliary labels: take with a full glass of water, take on an empty stomach, avoid dairy, iron, antacids, do not lie down for at least 30 minutes after taking

Question 2

Mechanism of Action

Answer 2

Antiresorptive agents
Inhibit osteoclast activity
Osteoclasts=cells responsible for bone resorption
Suppress bone turnover and bone loss

Question 3

Fosamax

Answer 3

Generic name: alendronate
10mg tablets: once daily
70mg tablets: once weekly

Question 4

Actonel

Answer 4

Generic name: risedronate
35mg tablets: once weekly
150mg tablets: once monthl