Incretin Mimetics, Glucagon-Like Peptide Receptor Agonists (GLP-1 Agonists) Flashcards

1
Q

Common Facts

A

Common ending: -tide

Commonly used to treat: type II diabetes mellitus

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2
Q

Mechanism of Action

A

Stimulate GLP-1 (glucagon-like peptide) receptors in alpha and beta cells in pancreas

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2
Q

Mechanism of Action

A

Stimulate GLP-1 (glucagon-like peptide) receptors in alpha and beta cells in pancreas
-Beta cell stimulation mediates insulin secretion when glucose
levels increase
Delay gastric emptying
-Causes decreased appetite
-Slows rise of post-prandial blood glucose levels

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3
Q

Byetta

A

Generic name: exenatide
Subcutaneous injection
Inject 60 minutes before morning and evening meal

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