Incretin Mimetics, Glucagon-Like Peptide Receptor Agonists (GLP-1 Agonists) Flashcards
1
Q
Common Facts
A
Common ending: -tide
Commonly used to treat: type II diabetes mellitus
2
Q
Mechanism of Action
A
Stimulate GLP-1 (glucagon-like peptide) receptors in alpha and beta cells in pancreas
2
Q
Mechanism of Action
A
Stimulate GLP-1 (glucagon-like peptide) receptors in alpha and beta cells in pancreas
-Beta cell stimulation mediates insulin secretion when glucose
levels increase
Delay gastric emptying
-Causes decreased appetite
-Slows rise of post-prandial blood glucose levels
3
Q
Byetta
A
Generic name: exenatide
Subcutaneous injection
Inject 60 minutes before morning and evening meal