Beta Adrenergic Antagonist Flashcards
Common Facts
Common name: Beta (B) blocker
Common ending: -olol
Commonly used to treat: cardiovascular conditions (hypertension)
Mechanism of Action
Reduce heart’s workload
Decrease heart’s demand for oxygen by decreasing force of contraction (cardiac output)
Binds to beta receptors
Notes
Beta(1) receptors are located in cardiac tissue
Beta(2) receptors are located in pulmonary tissue
Selective beta blockers are selective for beta(1) receptors. Binding to beta(1) receptors produces cardiac stimulation
Non-selective beta blockers bind to both beta(1) and beta(2) receptors. Binding to beta(2) receptors can cause bronchospasm and are contraindicated in patients with asthma or COPD
Common Adverse Reaction
Hypotension Dizziness Bradycardia Fatigue Abrupt discontinuation can produce tachycardia
Common Auxiliary Labels
May cause dizziness
Avoid abrupt discontinuation/Do not discontinue without medical supervision
Do not crush/chew (This is for sustained or extended release formulations)
Blocadren
Non-Selective Beta Blockers
Generic name: timolol
Tablets: 5mg, 10mg, 20mg
Corgard
Non-Selective Beta Blockers
Generic name: nadolol
Tablets: 40mg, 80mg, 160mg
Also commonly used to treat: angina
Inderal
Generic name: propranolol
Tablets: 10mg, 20mg, 40mg, 80mg, 120mg
LA capsules: 60mg, 120mg
Also commonly used to treat: angina, arrhythmia
Sotacor
Generic name: sotalol
Tablets: 80mg, 160mg
Visken
Generic name: pindolol
Tablets: 5mg, 10mg, 15mg
Coreg
Non-selective beta blockers+alpha blockers
Generic name: carvedilol
Tablets: 3.125mg, 6.25mg, 12.5mg, 25mg
Often dosed BID
Also commonly used to treat: heart failure
Auxiliary label(s): take with food
Trandate
Non-Selective Beta Blockers + Alpha Blockers
Generic name: labetalol
Tablets: 100mg, 200mg
Lopressor
Selective Beta Blockers
Generic name: metoprolol
Tablets: 25mg, 50mg, 100mg
Note: 25mg tablets are not covered by ODB
12.5mg is often prescribed (must use either 25mg or 50mg tablets)
Often dosed once daily or BID
SR tablets: 100mg, 200mg
Often dosed once daily (QAM)
Also commonly used to treat: angina, heart failure
Auxiliary label(s): take with food (regular tablets)
Monitan, Rhotral, Sectral
Generic name: acebutolol
Tablets: 100mg, 200mg, 400mg
Also commonly used to treat: Arrhythmia
Monocor
Generic name: bisoprolol
Tablets: 5mg, 10mg
Often dosed once daily (QAM)
Also commonly used to treat: Heart failure
Note: 2.5mg once daily is so often prescribed (must split 5mg tablets)