Angiotensin II Receptor Antagonist or Angiotensin II Receptor Blocker Flashcards
Common Facts
Common Name: ARBs
Common ending: -sartan
Commonly used to treat: cardiovascular conditions (hypertension)
Mechanism of Action
Competitive antagonist at angiotensin II receptor site
Block binding of angiotensin II (Angiotensin II=potent vasocontrictor)
Notes
Similar effectiveness as ACEIs but do not cause accumulation of bradykinins or dry cough
First choice for treatment of hypertension in patients with diabetes or Coronary Artery Disease (CAD) in patients who cannot tolerate ACEIs
Contraindicated in second and third trimesters of pregnancy
Interfere with fetal development of kidneys and may cause fetal death
Common Adverse Reaction
Dizziness
Dry mouth
Common Auxiliary Labels
May cause dizziness or lightheadness
Common Dosing
Most often once daily dosing (QAM)
Atacand
Generic name: candesartan
Tablets: 4mg, 8mg, 16mg, 32mg
Avapro
Generic name: irbesartan
Tablets: 75mg, 150mg, 300mg
Cozaar
Generic name: losartan
Tablets: 25mg, 50mg, 100mg
Diovan
Generic name: valsartan
Tablets: 40mg, 80mg, 160mg, 320mg
Micardis
Generic name: telmisartan
Tablets: 40mg, 80mg
Olmetec
Generic name: olmesartan
Tablets: 20mg, 40mg
