Neuroleptics

Question 1

Common Facts

Answer 1

Common name: antipsychotics

Commonly used to treat: schizophrenia

Question 2

Mechanism of Action

Answer 2

Decrease dopamine (DA)
Dopamine=neurotransmitter

Question 3

Potential Adverse Reaction

Answer 3

Parkinson-like symptoms
Weight gain
Orthostatic hypotension
Sedation
Neuroleptic Malignant Syndrome
     -Rate, but life threatening
     -Muscle rigidity, increased body temperature, fluctuating consciousness, 
      renal failure

Question 4

Largactil

Answer 4

Generic name: chlorpromazine

Tablets: 25mg, 50mg, 100mg

Question 5

Trilafon

Answer 5

Generic name: perphenazine

Tablets: 2mg, 4mg, 8mg, 16mg

Question 6

Stelazine

Answer 6

Generic name: trifluoperazine

Tablets: 1mg, 2mg, 5mg, 10mg

Question 7

Haldol

Answer 7

Generic name: haloperidol

Tablets: 0.5mg, 1mg, 5mg, 10mg, 20mg

Question 8

Clozaril

Answer 8

Generic name: clozapine
Tablets: 25mg, 100mg
Restricted use; patients require regular blood work
Adverse reaction drug: agranulocytosis (fatal drop in number of white blood cells)

Question 9

Zyprexa, Zyprexa Zydis

Answer 9

Generic name: olanzapine
Tablets: 2.5mg, 5mg, 7.5mg, 10mg, 15mg, 20mg
ODT (oral disintegrating tablets): 5mg, 10mg, 15mg, 20mg

Question 10

Risperdal

Answer 10

Generic name: risperidone
Tablets: 0.25mg, 0.5mg, 1mg, 2mg, 3mg, 4mg
ODT (Oral disintegrating tablets): 0.5mg, 1mg, 2mg, 3mg, 4mg

Question 11

Invega

Answer 11

Generic name: paliperidone

ER tablets: 3mg, 6mg, 9mg

Question 12

Invega

Answer 12

Generic name: paliperidone

ER tablets: 3mg, 6mg, 9mg

Question 13

Seroquel

Answer 13

Generic name: quetiapine
Tablets: 25mg, 100mg, 200mg, 300mg
XR tablets: 50mg, 150mg, 200mg, 300mg, 400mg
XR auxiliary label: swallow whole, do not crush or chew

Question 14

Zeldox

Answer 14

Generic name: ziprasidone

Tablets: 20mg, 40mg, 60mg, 80mg

Question 15

Abilify

Answer 15

Generic name: aripiprazole

Tablets: 2mg, 5mg, 10mg, 15mg, 20mg, 30mg