PHARM Pharmacology & Physiology of Stroke Flashcards
1
Q
2 types of stroke
A
- Ischaemic stroke
- Haemorrhagic stroke
2
Q
Ischaemic stroke
A
Occlusion of a blood vessel by thrombus.
3
Q
Haemorrhagic stroke
A
Rupture of a blood vessel
4
Q
Symptoms of stroke
A
Changes in:
Vision, language, numbness/weakness/paralysis, dizziness, swallowing, headache.
5
Q
Link morphological & biochemical changes to the ischaemic cascade
A
Infarction - ionic failure, anoxic depolarisation, reduced glucose consumption, glutamate release
Inflammation & apoptosis - reduced protein synthesis, acidosis, increased oxygen extraction, selective gene expression.