PHARM Pharmacology & Physiology of Stroke Flashcards

1
Q

2 types of stroke

A
  1. Ischaemic stroke
  2. Haemorrhagic stroke
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2
Q

Ischaemic stroke

A

Occlusion of a blood vessel by thrombus.

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3
Q

Haemorrhagic stroke

A

Rupture of a blood vessel

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4
Q

Symptoms of stroke

A

Changes in:
Vision, language, numbness/weakness/paralysis, dizziness, swallowing, headache.

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5
Q

Link morphological & biochemical changes to the ischaemic cascade

A

Infarction - ionic failure, anoxic depolarisation, reduced glucose consumption, glutamate release
Inflammation & apoptosis - reduced protein synthesis, acidosis, increased oxygen extraction, selective gene expression.

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