PHARM Inotropic Agents Flashcards

1
Q

Basic PHYS behind right heart failure symptoms

A

Oedema, JVP elevation, hepatomegaly due to back pressure in systemic circulation.

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2
Q

Basic PHYS behind left heart failure symptoms

A

Dyspnoea, orthopnea, oedema, tachycardia due to back pressure to pulmonary circulation.

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3
Q

Preload vs afterload

A

Preload - stretch of ventricular muscle (increased by increasing blood volume, venoconstriction)
Afterload - resistance to ventricular emptying (increased by arterial/peripheral vasoconstriction)

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4
Q

Effect of preload and afterload on CO

A

Preload - increase CO
Afterload - decrease CO

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5
Q

Effect of diastolic heart failure on CO

A

Preserved CO @ rest, reduced CO @ exercise.
HFpEF

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6
Q

Effect of systolic heart failure on CO

A

Reduced CO
HFrEF

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