PHARM Cardiac Biomarkers

Question 1

When is cardiac troponin detected?

Answer 1

4-10hrs after AMI

Question 2

When does cardiac troponin peak?

Answer 2

12-48hrs after AMI

Question 3

For how long is cardiac troponin abnormal?

Answer 3

4-10 days post MI

Question 4

ANP, BNP, CNP locations of release.

Answer 4

Natriuretic peptides
* ANP (found in the atrium)
* BNP (found in the ventricle)
* CNP (found in the endothelium).

Question 5

CRP

Answer 5

C-Reactive Protein synthesised in the liver, stimulated by IL-6 from inflammatory cells, binds to surface of dying cells to activate complement system & promote phagocytosis, predictive of inflammation/CVD.