Pedia: Neonatology Flashcards

1
Q

At what week of gestation is surfactant first synthesized? First appears in amniotic fluid? Reach mature levels?

A

20W
28-32W
35W

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2
Q

Serious apnea is defined as cessation of breathing _____

A

Longer than 20s

Of any duration accompanied by cyanosis and bradycardia

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3
Q

Idiopathic apnea of prematurity resolves by ___

A

36W PCA

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4
Q

How does one differentiate CHD from pulmonary diseases as the underlying cause of cyanosis?

A

Hyperopia test.

PaO2 increases with pulmonary disease; not increased in cyanotic.

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5
Q

Management of biliary atresia

A

Kasai procedure

Do it before 8W (90% success)

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6
Q

Abdominal UTZ finding in biliary atresia

A

Triangular cord sign

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7
Q

How does one differentiate neonatal hepatitis from biliary atresia?

A

Neonatal hepatitis more common in premature; with a familial tendency.
Consistently pigmented stools rule against biliary atresia

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8
Q

Most common syndrome with intrahepatic duct paucity

A

Alagile syndrome

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9
Q

Kernicterus occurs in infants with a bilirubin level ___

A

20mg/dL

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10
Q

Jaundice is observed in how many % of term infants? Preterm infants?

A

60% of term;

80% of preterm

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11
Q

Indicators of pathologic jaundice

A

Appear within 1st 24 hours
Normal rate of increase 12 in full term; >14 in preterm
Persists after 10-14 days
Direct bilirubin fraction >2mg/dL

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12
Q

Most common location of Bochdalek’s hernia? Morgagni?

A

Bochdalek: posterolateral, left
Morgagni: antermedial, right

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13
Q

Triad of necrotizing enterocolitis:

A
  • Intestinal ischemia
  • Bacterial translocation
  • Enteral nutrition
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14
Q

Indications for surgery in necrotizing enterocolitis:

A
  • Evidence of perforation on X-ray

- positive result of abdominal paracentesis

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15
Q

Most common cause of nosocomial infections in neonates

A

Coagulase negative staphylococcus

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16
Q

What is the most common cause of neonatal hepatitis?

A

Group B streptococcus

17
Q

Small salmon pink papules in neonates suggest infection with

A

Listeria monocytogenes

18
Q

Drug of choice for neonatal meningitis caused by enterovirus

A

Pleconaril

19
Q

What do you give in neonatal resuscitation if mother received narcotic within 4 hours of delivery

A

Naloxone

20
Q

Treatment for recurrent apnea of prematurity

A

Theophylline or caffeine

Lowers threshold of response to hypercapnia;
Enhances diaphragmatic contractility;
Prevents diaphragm fatigue