Pathology - reproductive pathology

Question 1

. A 29 year old woman has intermittent abdominal pain and has had difficulty getting
pregnant. Laparoscopy shows several small brown/red lesions on the peritoneal
surface which are removed. Histology shows endometrial gland, stroma and
haemorrhage.
Which is the most likely diagnosis?
A. Endometrial hyperplasia
B. Endometriosis
C. Metastatic endometrial carcinoma
D. Uterine fibroidsa
E. Polycystic ovary syndrome

Answer 1

qB. Endometriosis

Question 2

2. A 28 year old woman has irregular periods, severe acne and excessive facial hair.
   Her periods started at age 15 and occur irregularly. Her BMI is 32 kg/m2.
   Which is the most likely diagnosis?
   A. Bulimia nervosa
   B. Hashimoto’s thyroiditis
   C. Iatrogenic Cushing’s syndrome
   D. Pelvic inflammatory disease
   E. Polycystic ovary syndrome

Answer 2

E. Polycystic ovary syndrome

Question 3

. A 28 year old woman attends the emergency department with right sided abdominal
pain and is found to have a right tubal ectopic pregnancy.
What is the most common recognised predisposing risk factor for this
condition?
A. Acute pyelonephritis
B. Diverticular disease
C. Pelvic inflammatory disease
D. Inflammatory bowel disease
E. Molar pregnancy

Answer 3

C. Pelvic inflammatory disease

Question 4

4. A 25 year old woman has severe vomiting. Her last period was 9 weeks ago.
   Investigations:
   A urinary pregnancy test is positive.
   Beta HCG 500,000 IU/L (<10)
   Transabdominal ultrasound: Fetal pole is not seen. Uterus 16 weeks sized with the cavity full of
   small cystic grape like lesions = “snow storm” appearance.
   Which is the most likely diagnosis?
   A. Adenomyosis
   B. Ectopic pregnancy
   C. Hydatidiform mole
   D. Polycystic ovarian syndrome
   E. Uterine fibroids

Answer 4

C. Hydatidiform mole

Question 5

what is the prescense of endometrial mucosa within the myometrium (which breaks down normally each menstrual cycle causing painful and prolonged periods) known as ?

a.adenomyosis
b.PCOS
c.endometriosis
d.fibroids
e.pelvic inflammatory disease

Answer 5

a.adenomyosis

Question 6

patient has prolonged and severe knifelike pain during periods
histologicy shows prescence of endometrial stroma and glandular tissue within the smooth muscle of the myometrium resulting in hypertrophy of the surrounding myometrium
which condition most likely

a.adenomyosis
b.PCOS
c.endometriosis
d.fibroids
e.pelvic inflammatory disease

Answer 6

a.adenomyosis

Question 7

patient has a missed period in combination with one sided low tummy pain , vaginal bleeding and pain in the tip of her shoulder , past medical history of pelvic inflammatory disease
what do these symptoms indicate

a.adenomyosis
b.ectopic pregnancy
c.endometriosis
d.fibroids
e.pelvic inflammatory disease

Answer 7

b.ectopic pregnancy

Question 8

female patient has pain in lower tummy and back worsening with periods, pain during sex, pain using toilet during periods and has had past difficulty getting pregnant

histology shows endometrial tissue located ectopically consisting of endometrial type glands and stroma

which condition is this associated with

a.adenomyosis
b.PCOS
c.endometriosis
d.fibroids
e.pelvic inflammatory disease

Answer 8

c.endometriosis

Question 9

what is a non cancerous growth developed in or around the uterus known as (mostly asymptomatic)

a.adenomyosis
b.PCOS
c.endometriosis
d.fibroids
e.pelvic inflammatory disease

Answer 9

d.fibroids

Question 10

fibroids develop more frequently in which group

a.young women
b.old women
c.women of african carribean origin
d.women of asian origin

Answer 10

c.women of african carribean origin

Question 11

a fibroid in the muscle wall of the womb is known as ..

a.intramural
b.subserosal
c.submucosal

Answer 11

a.intramural

Question 12

a fibroid outside the wall of the uterus into the pelvis is known as..

a.intramural
b.subserosal
c.submucosal

Answer 12

b.subserosal

Question 13

a fibroid in the myometrium growing into the uterine cavity is known as..

a.intramural
b.subserosal
c.submucosal

Answer 13

c.submucosal

Question 14

women has no symptoms
histologically a round well circumsised solid nodule that is white/tan in colour is seen
what does this indicate

a.adenomyosis
b.PCOS
c.endometriosis
d.fibroids
e.pelvic inflammatory disease

Answer 14

d.fibroids

Question 15

an infection of one or more reproductive organs is known as

a.adenomyosis
b.PCOS
c.endometriosis
d.fibroids
e.pelvic inflammatory disease

Answer 15

e.pelvic inflammatory disease

Question 16

young female patient with pelvic pain and fever, history of being sexually active, laparoscopic evaluation is done to diagnose which condition

a.adenomyosis
b.PCOS
c.endometriosis
d.fibroids
e.pelvic inflammatory disease

Answer 16

e.pelvic inflammatory disease

Question 17

a complication of pregnancy characterised by abnormal trophoblasts (normally develop placenta) is known as

A. Adenomyosis
B. Ectopic pregnancy
C. Hydatidiform mole
D. Polycystic ovarian syndrome
E. Uterine fibroids

Answer 17

C. Hydatidiform mole

Question 18

irregular periods, difficulty getting pregnant, excessive hair growth and weight gain are characteristic of which condition

A. Adenomyosis
B. Ectopic pregnancy
C. Hydatidiform mole
D. Polycystic ovarian syndrome
E. Uterine fibroids

Answer 18

D. Polycystic ovarian syndrome

Question 19

which of these is an example of a gestational trophoblastic disease charcaterised by vomiting and nausea in pregnancy, abnormal vaginal bleeding and pain/pressure on the pelvis

A. Adenomyosis
B. Ectopic pregnancy
C. Hydatidiform mole
D. Polycystic ovarian syndrome
E. Uterine fibroids

Answer 19

C. Hydatidiform mole

Question 20

in GTD abnormal forms of which cell type grow inside the uterus after conception

a.cytotrophoblasts
b.syncitiotrophoblasts
c.trophoblasts

Answer 20

c.trophoblasts

Question 21

severe nausea and vomiting in pregenancy, vaginal bleeding,pain / pressure in the pelvis are symptoms of what condition

A. Adenomyosis
B. Ectopic pregnancy
C. gestational trophoblastic disease
D. Polycystic ovarian syndrome
E. Uterine fibroids

Answer 21

C. gestational trophoblastic disease