Parvoviridae

Question 1

Morphology

Answer 1

linear ssDNA - self promoting
hairpin ends
icoshederal capsid

non - enveloped

Parvus- small

Question 2

Resistance

Answer 2

very strong

Question 3

Biological properties

Answer 3

Baltimore II.
•cellular polymerase - multiplication in dividing cells •complementation – adeno- or herpesvirus infected cells
• hemagglutination • stenoxen

Question 4

Genus

Answer 4

Subfamilies:
Densovirinae
Parvovirinae:
- Proto-, Avi-, Amdo-, Boca-, Copi-, Tetra-, Erythro-, Dependoparvovirus

Question 5

Protoparvovirus

Answer 5

•Porcine parvovirus – SMEDI
→ Stillbirth, Mummification, Embryonic Death, Infertility

• Canine parvovirus 2 – enteritis, myocarditis, exsiccosis
• Feline panleukopenia virus – panleukopenia

Question 6

Bocavirus

Answer 6

• Bovine parvovirus

* Canine minute virus (CPV-1)

Question 7

Amdovirus

Answer 7

• Aleutian mink disease virus

* immunocomplex disease – hemorrhage, nephritis

Question 8

Erythrovirus

Answer 8

•B 19 virus:
human transient aplastic crisis, fetal wastage (hydrops)

•Simian erythroviruses

Question 9

Dependovirus

Answer 9

•Adeno associated viruses (human, canine, bovine, ect.)

•Goose parvovirus – Derzsy’s disease:
- ascites, respiratory disease, enteritis

Question 10

Diagnosis

Answer 10

• isolation in dividing cells – intranuclear inclusion bodies •HA, IF, AGID
• Serology: HAI, VN

Question 11

Antigenetic properties

Answer 11

•very good antigens – long immunity
•cross reactions – cross immunity
→ related viruses (mutants) – panleukopenia, mink enteritis, canine parvovirus 2

Question 12

Densovirinae

Answer 12

•arthropod pathogens