Mononegavirales: Bornaviridae Flashcards
1
Q
Morphology
A
- -ssRNA genome
- helical capsid
- enveloped, ~100 nm
(borna)
2
Q
Resistance
A
weak
3
Q
Biological properties
A
Baltimore V
• host specificity: ?
• reservoir: shrews, rodents?
• only in restricted geographic areas: Europe (Japan?)
4
Q
Antigenic properties
A
good antigens
5
Q
Diagnosis
A
- clinical signs, histopathology lesions (nuclear inclusions)
- RT-PCR
6
Q
Genus
A
Bornavirus genus
7
Q
Bornavirus genus
A
Borna disease
•encephalitis, encephalosis (HORSE, sheep, cattle, dog, human ???)
Avian bornaviruses: parrot proventricular dilatation disease